Obana Kyle K, Lin Adrian J, Yang Joshua, Ryan Deirdre D, Goldstein Rachel Y, Kay Robert M
Children's Orthopedic Center, Children's Hospital Los Angeles.
Children's Bone and Spine Surgery, Las Vegas, NV.
Medicine (Baltimore). 2020 Jan;99(1):e18613. doi: 10.1097/MD.0000000000018613.
Postoperative fever in pediatric patients following reconstructive hip surgery is of unknown significance. This study identifies the prevalence of postoperative fever after corrective hip surgery, its relationship to infection, and whether preventative use of anti-pyretics affects patient outcomes.Overall, 222 patients who underwent a varus derotational osteotomy (VDRO) between 11/1/2004 to 8/1/2014 with minimum 6 months follow up were retrospectively identified. Variables included diagnosis, inpatient stay, daily maximum temperature, duration of fever, fever workup, and administration of scheduled anti-pyretics. Fever was defined as temperature ≥38°C.In total, 123/222 (55.4%) and 70/222 (31.5%) had postoperative fevers of ≥38°C and ≥38.5°C, respectively. Average inpatient stay was 2.7 days postoperatively. Temperature (mean = 38.0°C) was greatest on postoperative day 1 (POD1), and 43.7% of patients had T ≥38°C on POD1. Anti-pyretics did not influence the duration of fever. Anti-pyretics on the day of surgery (POD0) did not influence the incidence of fever. Acetaminophen on POD0 significantly reduced likelihood of fever on POD1 (P = .02). Average length of fevers ≥38°C and 38.5°C were 8.4 and 4.2 hours, respectively. 3/18 (16.7%) fever workups administered were positive. Postoperative fever did not predict infection. 9/222 (4/1%) patients had postoperative infection - 5/123 (4.1%) with fever ≥38°C and 4/70 (5.7%) with fever ≥38.5°C. Rates of infection in patients with and without fevers were not significantly different (P = .97 for T ≥38°C and P = .38, for T ≥38.5°C).Though common, postoperative fever does not increase risk of infection. The low prevalence of positive cultures indicates routine fever workups can safely be avoided in most patients.Level of Evidence: III, retrospective comparative study.
小儿髋关节重建手术后的发热意义不明。本研究确定了矫正性髋关节手术后发热的发生率、其与感染的关系,以及预防性使用退烧药是否会影响患者预后。总体而言,对2004年11月1日至2014年8月1日期间接受内翻旋转截骨术(VDRO)且随访至少6个月的222例患者进行了回顾性分析。变量包括诊断、住院时间、每日最高体温、发热持续时间、发热检查以及定期退烧药的使用情况。发热定义为体温≥38°C。总共,123/222(55.4%)和70/222(31.5%)的患者术后发热分别≥38°C和≥38.5°C。术后平均住院时间为2.7天。体温(平均=38.0°C)在术后第1天(POD1)最高,43.7%的患者在POD1时体温≥38°C。退烧药不影响发热持续时间。手术当天(POD0)使用退烧药不影响发热发生率。POD0时使用对乙酰氨基酚显著降低了POD1时发热的可能性(P=0.02)。体温≥38°C和≥38.5°C的发热平均时长分别为8.4小时和4.2小时。18次发热检查中有3次(16.7%)结果呈阳性。术后发热不能预测感染情况。222例患者中有9例(4.1%)发生术后感染,体温≥38°C的患者中有5例(4.1%),体温≥38.5°C的患者中有4例(5.7%)。发热和未发热患者的感染率无显著差异(体温≥38°C时P=0.97,体温≥38.5°C时P=0.38)。虽然术后发热常见,但并不会增加感染风险。阳性培养结果的低发生率表明,大多数患者可安全避免常规发热检查。证据级别:III级,回顾性比较研究。