Section of Pediatric Nephrology, Children's Hospital Colorado, University of Colorado, Aurora, CO, USA.
Clinical Nutrition Department, Children's Hospital Colorado, Aurora, CO, USA.
Pediatr Nephrol. 2021 Jan;36(1):51-63. doi: 10.1007/s00467-019-04428-y. Epub 2020 Jan 2.
Dyslipidemia after kidney transplantation is a common complication that has historically been underappreciated, especially in pediatric recipients. It is also a major modifiable risk factor for cardiovascular disease, a top cause of morbidity and mortality of transplant patients. While most knowledge about post-transplant dyslipidemia has been generated in adults, recommendations and treatment strategies also exist for children and are presented in this review. Awareness of these applicable guidelines and approaches is required, but not sufficient, for the reliable management of dyslipidemia in our patients, and additional needs and opportunities for comprehensive care in this area (e.g., quality improvement) are outlined.
肾移植后血脂异常是一种常见的并发症,但在过去并未得到充分重视,尤其是在儿科受者中。它也是心血管疾病的一个主要可改变的危险因素,而心血管疾病是导致移植患者发病率和死亡率居高不下的首要原因。尽管大多数关于移植后血脂异常的知识都是在成人中获得的,但也有针对儿童的建议和治疗策略,本综述对此进行了介绍。了解这些适用的指南和方法对于我们的患者可靠地管理血脂异常是必要的,但还不够,还需要在该领域(例如,质量改进)全面了解并把握患者的护理需求和机会。