Pecoraro Felice, Dinoto Ettore, Pakeliani David, Ferlito Francesca, Mirabella Domenico, Lachat Mario, Farina Arduino, Bajardi Guido
University of Palermo, Department of Surgical, Oncological and Oral Sciences (Di.Chir.On.S.), Palermo, Italy; Vascular Surgery Unit, Palermo, Italy.
Vascular Surgery Unit, Palermo, Italy.
Ann Vasc Surg. 2020 Jul;66:667.e9-667.e14. doi: 10.1016/j.avsg.2019.12.019. Epub 2020 Jan 2.
The aim of this study was to report the feasibility and outcomes with the endovascular treatment of spontaneous internal carotid artery dissections (ICADs) using a proximal embolic protection device (EPD).
This is a retrospective analysis of patients treated for spontaneous symptomatic ICAD using a proximal EPD from January 2017 to December 2018. Indication for treatment was the presence of neurologic symptoms. Early outcomes measured included technical success, perioperative mortality, and major cardiovascular or cerebrovascular complications. Late outcomes were recurrent neurologic symptoms, patency, and reinterventions.
A total of 4 male patients with ICAD were included. A preoperative cerebral computed tomography positive for cerebral ischemic events was reported in all cases. In 3 patients, the neurologic symptoms consisted of a transient ischemic attack; the remaining patient presented an amaurosis fugax and aphasia. In 2 patients, ICAD was associated with a carotid significant stenosis. In all patients, the reported approach was feasible with no complications and complete anatomic dissection resolution. At a mean follow-up of 18 months, all stents are patent and no restenosis recurrence or complications were registered.
The use of proximal EPDs allowed the treatment of ICAD under flow arrest, minimizing the risk of stroke during the endovascular maneuvers. Larger series are required to validate this treatment strategy.
本研究的目的是报告使用近端栓塞保护装置(EPD)对自发性颈内动脉夹层(ICAD)进行血管内治疗的可行性和结果。
这是一项对2017年1月至2018年12月期间使用近端EPD治疗自发性症状性ICAD患者的回顾性分析。治疗指征为存在神经系统症状。测量的早期结果包括技术成功率、围手术期死亡率和主要心血管或脑血管并发症。晚期结果为复发性神经系统症状、通畅率和再次干预情况。
共纳入4例ICAD男性患者。所有病例术前脑部计算机断层扫描均显示脑缺血事件阳性。3例患者的神经系统症状为短暂性脑缺血发作;其余1例患者出现一过性黑矇和失语。2例患者的ICAD与颈动脉严重狭窄有关。所有患者的报告方法均可行,无并发症,解剖夹层完全消退。平均随访18个月时,所有支架均通畅,未记录到再狭窄复发或并发症。
使用近端EPD可在血流阻断下治疗ICAD,将血管内操作期间的中风风险降至最低。需要更大规模的系列研究来验证这种治疗策略。