Shiraz Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
World J Surg Oncol. 2020 Jan 6;18(1):7. doi: 10.1186/s12957-019-1781-7.
Ex situ liver resection and autotransplantation is among the most advanced techniques which has been introduced in recent years.
A 24-year-old male referred with chief complaints of abdominal pain, nausea, and vomiting from 1 month prior to admission. Computed tomography showed a large liver mass in the left lobe of the liver with involvement of retrohepatic inferior vena cava (IVC), in favor of hepatocellular carcinoma. After hepatectomy, the common bile duct was completely removed. A 4-cm Dacron graft was anastomosed to the inferior and top of the IVC. A temporary portocaval shunt was placed, and ex situ resection of the left lobe of the liver was done. Remnant of the liver was implanted. Reconstruction of the bile duct was done using a Roux-en-Y technique, and autotransplantation of the liver was then completed. During a 4-year follow-up, the patient had no complaints and is in good conditions.
With appropriate consideration of patients, despite surgical complexities, ex situ resection of unresectable HCC can provide excellent prognosis.
离体肝切除和自体移植是近年来引入的最先进技术之一。
一名 24 岁男性因腹痛、恶心和呕吐就诊,症状从入院前 1 个月开始出现。计算机断层扫描显示左肝叶有一个大的肝肿块,伴有肝后下腔静脉(IVC)受累,考虑为肝细胞癌。肝切除术后,胆总管被完全切除。将 4 厘米的涤纶移植物吻合到 IVC 的下侧和顶部。放置临时门腔静脉分流术,并进行离体左肝叶切除术。剩余的肝脏被植入。使用 Roux-en-Y 技术进行胆管重建,然后完成肝脏自体移植。在 4 年的随访中,患者无任何不适,状况良好。
尽管手术复杂,但对于不可切除的 HCC 患者,适当考虑后进行离体肝切除可提供良好的预后。