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评价一项全卫生系统的、由药剂师主导的急诊科实验室随访和抗菌药物管理项目。

Evaluation of a health system-wide pharmacist-driven emergency department laboratory follow-up and antimicrobial management program.

机构信息

Department of Pharmacy, Cleveland Clinic, Cleveland, OH, United States of America.

Department of Pharmacy, Cleveland Clinic, Cleveland, OH, United States of America.

出版信息

Am J Emerg Med. 2020 Dec;38(12):2591-2595. doi: 10.1016/j.ajem.2019.12.052. Epub 2019 Dec 27.

Abstract

BACKGROUND

Emergency Department (ED) follow-up programs ensure that cultures, laboratory studies, and empiric antimicrobials are appropriately managed post-discharge. We sought to provide a comprehensive assessment of a pharmacist-driven laboratory follow-up process in a large, integrated health system.

METHODS

A retrospective, observational review of 13 EDs was conducted. Patients were included if they had a laboratory study sent from the ED between December 1, 2017 and May 31, 2018 that did not result while the patient was in the ED. Microbiology results analyzed were urine, wound, respiratory, stool, throat, bacterial vaginosis, vaginal candidiasis, and sexually transmitted infections (STI). Examples of laboratory results assessed were metabolic panels and drug levels. The primary objective was to quantify the number of interventions made by pharmacists.

RESULTS

During a 6-month period, pharmacists reviewed 9107 microbiology results and 6211 laboratory results. The majority of results were urine cultures (3998, 50.6%) followed by STI results (1198, 15.2%). Of 7663 encounters, 39.8% required interventions and/or follow-up with a total of 3049 interventions made and 3333 patients educated. The most common interventions were initiation of therapy (1629, 53.4%), change in medication (505, 16.6%), and follow-up with a clinician (322, 10.6%). Pharmacists reviewed microbiology results and completed interventions in a median of 25.3 h from the time the result was received in the electronic health record.

CONCLUSION

Almost 40% of ED encounters required an intervention after discharge. A pharmacist led laboratory follow-up program is an important adjunct to facilitating stewardship and culture management in the ED.

摘要

背景

急诊部(ED)随访计划确保在出院后妥善管理培养物、实验室研究和经验性抗菌药物。我们旨在为大型综合卫生系统中由药剂师驱动的实验室随访流程提供全面评估。

方法

对 13 个 ED 进行回顾性观察性研究。纳入标准为:2017 年 12 月 1 日至 2018 年 5 月 31 日期间从 ED 发出但在 ED 期间未出结果的实验室研究的患者。分析的微生物学结果包括尿液、伤口、呼吸、粪便、喉咙、细菌性阴道病、阴道念珠菌病和性传播感染(STI)。评估的实验室结果示例包括代谢组学和药物水平。主要目标是量化药剂师的干预次数。

结果

在 6 个月期间,药剂师审查了 9107 份微生物学结果和 6211 份实验室结果。结果主要是尿液培养物(3998,50.6%),其次是 STI 结果(1198,15.2%)。在 7663 次就诊中,39.8%需要干预和/或与临床医生跟进,共进行了 3049 次干预和 3333 次患者教育。最常见的干预措施是开始治疗(1629,53.4%)、改变药物(505,16.6%)和与临床医生跟进(322,10.6%)。药剂师从电子健康记录收到结果后中位数 25.3 小时审查微生物学结果并完成干预。

结论

近 40%的 ED 就诊需要在出院后进行干预。由药剂师主导的实验室随访计划是促进 ED 中管理和培养物管理的重要辅助手段。

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