短期利血平治疗对全身性和局灶性肌张力障碍-运动障碍综合征的影响。
Effects of short-term reserpine treatment on generalized and focal dystonic-dyskinetic syndromes.
作者信息
Raffaele R, Patti F, Sciacca A, Palmeri A
机构信息
Institute of Neurology, University of Catania, Italy.
出版信息
Funct Neurol. 1988 Jul-Sep;3(3):327-35.
We report that low dose reserpine treatment (0.25 mg/day for 7 days) improves the dystonic-dyskinetic disability score in patients affected by idiopathic dystonias, iatrogenic dystonic-dyskinetic syndromes and Sydenham's chorea. The results support the idea that the particular antidopaminergic activity exerted by reserpine or other dopamine-depleting agents may produce good therapeutical efficacy, although reserpine can precipitate Parkinsonism and induce dopamine-receptor supersensitivity.
我们报告，低剂量利血平治疗（0.25毫克/天，持续7天）可改善特发性肌张力障碍、医源性肌张力障碍-运动障碍综合征及小舞蹈病患者的肌张力障碍-运动障碍残疾评分。结果支持这样一种观点，即利血平或其他耗竭多巴胺的药物所具有的特定抗多巴胺能活性可能产生良好的治疗效果，尽管利血平可引发帕金森综合征并诱导多巴胺受体超敏反应。
Zotero 插件