Tabbut B R, Tessler H H, Williams D
Department of Ophthalmology, Eye and Ear Infirmary, University of Illinois College of Medicine, Chicago 60612.
Arch Ophthalmol. 1988 Dec;106(12):1688-90. doi: 10.1001/archopht.1988.01060140860027.
Fuchs' heterochromic iridocyclitis (FHI) is a frequently overlooked cause of anterior uveitis. Improper diagnosis may lead to unnecessary therapy. Dark brown irides may demonstrate heterochromia poorly. We believe that FHI may be overlooked in blacks because of a frequent lack of obvious heterochromia and the frequent presence of iris nodules. Heterochromia is not necessary for the diagnosis of FHI if other clinical features of the syndrome are present. In our series of 54 whites and 13 blacks with FHI, heterochromia occurred in 50 (92%) whites and ten (76%) blacks (nonsignificant difference). Iris nodules occurred in 11 (20%) whites and four (30%) blacks (not significant). Statistically significant differences occurred with cataract/aphakia in 41 (75%) whites and three (23%) blacks and with glaucoma in six (11%) whites and five (38%) blacks.
富克斯异色性虹膜睫状体炎（FHI）是前葡萄膜炎一个常被忽视的病因。诊断不当可能导致不必要的治疗。深棕色虹膜可能难以显示出色素不均。我们认为，由于常缺乏明显的色素不均且常出现虹膜结节，FHI在黑人中可能被忽视。如果存在该综合征的其他临床特征，则色素不均并非诊断FHI所必需。在我们的54例患有FHI的白人和13例黑人系列中，50例（92%）白人及10例（76%）黑人出现色素不均（无显著差异）。11例（20%）白人及4例（30%）黑人出现虹膜结节（无显著差异）。白内障/无晶状体在41例（75%）白人及3例（23%）黑人中出现，青光眼在6例（11%）白人及5例（38%）黑人中出现，二者均存在统计学显著差异。
