Frank R K, Bergeland M E
Veterinary Diagnostic Investigation, College of Veterinary Medicine, University of Minnesota, St. Paul 55108.
Avian Dis. 1988 Jul-Sep;32(3):574-82.
Two-to-5-week-old turkey poults from three large Minnesota flocks exhibited ataxia, flaccid paralysis, and up to 5% mortality as unexpected death. The major post-mortem finding was cerebellar hemorrhage and softening detected in 22 of 89 clinically affected poults. Histologic findings were severe focal or multifocal poliomyelomalacia in the lumbosacral intumescentia of the spinal cord, cerebellar malacia, and single-cell or multifocal coagulative necrosis of pancreatic acinar cells. Thirty of 32 clinically affected poults examined had microscopic spinal cord lesions, 12 of 48 had cerebellar lesions, and 26 of 47 had pancreatic lesions. Gross and microscopic cerebellar lesions resembled those of vitamin E deficiency in chicks. Hepatic selenium levels were approximately twice normal expected levels for poults.
来自明尼苏达州三个大型鸡群的2至5周龄火鸡幼雏出现共济失调、弛缓性麻痹，高达5%的意外死亡率。主要尸检发现是在89只临床患病幼雏中的22只检测到小脑出血和软化。组织学发现为脊髓腰膨大处严重的局灶性或多灶性脊髓软化、小脑软化以及胰腺腺泡细胞的单细胞或多灶性凝固性坏死。检查的32只临床患病幼雏中有30只存在脊髓微观病变，48只中有12只存在小脑病变，47只中有26只存在胰腺病变。大体和微观的小脑病变与雏鸡维生素E缺乏症的病变相似。肝脏硒水平约为火鸡正常预期水平的两倍。
