儿童膀胱神经母细胞瘤的罕见表现：一例报告。
Unusual presentation of bladder neuroblastoma in a child: A case report.
作者信息
Cai Jia-Bin, Wang Jin-Hu, He Min, Wang Fa-Liang, Xiong Jie-Ni, Mao Jun-Qing, Li Min-Ju, Zhu Kun, Liang Jia-Wei
机构信息
Division of Surgical Oncology, Department of Pediatric Surgery, Children's Hospital, Zhejiang University School of Medicine; National Clinical Research Center for Child Health, Hangzhou 310053, Zhejiang Province, China.
Department of Pathology, Children's Hospital, Zhejiang University School of Medicine; National Clinical Research Center for Child Health, Hangzhou 310053, Zhejiang Province, China.
出版信息
World J Clin Cases. 2020 Jan 6;8(1):194-199. doi: 10.12998/wjcc.v8.i1.194.
BACKGROUND
Neuroblastoma is an extracranial malignant tumor in children that is most often located in the adrenal gland and sympathetic ganglion. Here, we present a rare case of neuroblastoma originating from the urinary bladder.
CASE SUMMARY
A 3-year-old girl presented with lower abdominal pain with micturition. Ultrasound revealed a lower abdominal mass. Abdominal computed tomography scan displayed a solitary mass at the top of the urinary bladder. Blood levels of neuron-specific enolase and lactate dehydrogenase were elevated. We treated the child with partial cystectomy and six courses of chemotherapy, and the outcome at 4-year follow-up was unremarkable.
CONCLUSION
Neuroblastoma should be considered when tumors are located in the urinary bladder, especially in the dome; although this presentation is rare, the prognosis is very good.
背景
神经母细胞瘤是儿童期一种颅外恶性肿瘤，最常位于肾上腺和交感神经节。在此，我们报告一例罕见的起源于膀胱的神经母细胞瘤病例。
病例摘要
一名3岁女孩出现排尿时下腹部疼痛。超声检查发现下腹部有一肿块。腹部计算机断层扫描显示膀胱顶部有一个孤立性肿块。神经元特异性烯醇化酶和乳酸脱氢酶的血液水平升高。我们对该患儿进行了部分膀胱切除术和六个疗程的化疗，4年随访结果无异常。
结论
当肿瘤位于膀胱，尤其是膀胱顶部时，应考虑神经母细胞瘤；尽管这种表现罕见，但预后非常好。
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