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为分子生物物理学计算选择处理器。

Selecting a processor for computations in molecular biophysics.

作者信息

Bourne P E, Hendrickson W A

机构信息

Howard Hughes Medical Institute, Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032.

出版信息

Comput Biol Med. 1988;18(5):341-9. doi: 10.1016/0010-4825(88)90021-2.

Abstract

A number of relatively low-cost processors are now available which employ architectural features previously found only on very expensive supercomputers. The speed of these computers makes it possible to reduce the time to solution of certain problems and to resolve large problems that previously were too time consuming to perform locally. A brief overview of this type of processor is given and the implications for computations in molecular biophysics are discussed in reference to the results of a benchmark that uses the refinement of a protein structure from X-ray crystallographic data.

摘要

现在有一些成本相对较低的处理器,它们采用了以前仅在非常昂贵的超级计算机上才有的架构特性。这些计算机的速度使得缩短某些问题的求解时间以及解决以前在本地执行过于耗时的大问题成为可能。本文简要概述了这类处理器,并结合一项使用X射线晶体学数据对蛋白质结构进行优化的基准测试结果,讨论了其在分子生物物理学计算中的意义。

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