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通过定量光诱导荧光评估非龋洞性根龋病变——一项体内可行性研究。

Assessment of non-cavitated root caries lesions by quantitative light-induced fluorescence-An in vivo feasibility study.

作者信息

Günther Elena, Park Kyung-Jin, Meißner Thomas, Kottmann Tanja, Schmalz Gerhard, Haak Rainer, Ziebolz Dirk

机构信息

Department of Cariology, Endodontology and Periodontology, University Leipzig, Germany; Department of Prosthodontics, University Leipzig, Germany.

Department of Cariology, Endodontology and Periodontology, University Leipzig, Germany.

出版信息

Photodiagnosis Photodyn Ther. 2020 Jun;30:101671. doi: 10.1016/j.pdpdt.2020.101671. Epub 2020 Jan 24.

Abstract

OBJECTIVES

To evaluate the reproducibility of quantitative light-induced fluorescence (QLF) for the detection and assessment of demineralization states of non-cavitated root surfaces and to determine the correlation between visual inspection and QLF-analysis.

METHODS

46 exposed non-cavitated root surfaces of 12 participants were classified in three scores: sound (0), lesion ≤ 5 mm (1a), lesion > 5 mm in diameter (1b). Three examiners imaged every root surface three times using QLF (QRayCam) and measured fluorescence loss (ΔF) and lesion volume (ΔQ). The QLF-images were analyzed by three examiners. The intra- and interexaminer reproducibilities were calculated (intraclass correlation coefficient, ICC). The correlation between the scores of root caries and QLF-analysis was determined (rank correlation coefficient, Spearman-Rho ρ).

RESULTS

Intra- and interexaminer reproducibility (ICC) was 0.98 and 0.95 for ΔF, 0.94 and 0.91 for ΔQ, respectively. A significant correlation was observed between the scores and ΔF (ρ = -0.53, p < 0.01).

CONCLUSION

QLF as a reproducible diagnostic tool enables non-invasive detection and differentiation of non-cavitated root caries lesions on root surfaces in vivo. It can be recommended in addition to the clinical evaluation for prospective follow-up examinations of demineralization states of exposed root surfaces.

摘要

目的

评估定量光诱导荧光(QLF)检测和评估非龋洞型牙根表面脱矿状态的可重复性,并确定视觉检查与QLF分析之间的相关性。

方法

对12名参与者的46个暴露的非龋洞型牙根表面进行三分制评分:健康(0分)、病损≤5mm(1a分)、病损直径>5mm(1b分)。三名检查者使用QLF(QRayCam)对每个牙根表面进行三次成像,并测量荧光损失(ΔF)和病损体积(ΔQ)。三名检查者对QLF图像进行分析。计算检查者内和检查者间的可重复性(组内相关系数,ICC)。确定根龋评分与QLF分析之间的相关性(等级相关系数,Spearman-Rho ρ)。

结果

检查者内和检查者间的可重复性(ICC),ΔF分别为0.98和0.95,ΔQ分别为0.94和0.91。评分与ΔF之间存在显著相关性(ρ = -0.53,p < 0.01)。

结论

QLF作为一种可重复的诊断工具,能够在体内对牙根表面的非龋洞型根龋病变进行无创检测和鉴别。除了临床评估外,对于暴露牙根表面脱矿状态的前瞻性随访检查,推荐使用QLF。

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