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院前特征、发病率趋势及使用气体物质的紧急自伤患者的结局:日本大阪一项基于人群的描述性研究

Prehospital characteristics, incidence trends, and outcome of emergency self-inflicted injury patients with gas substances: a population-based descriptive study in Osaka, Japan.

作者信息

Katayama Yusuke, Matsuyama Tasuku, Kitamura Tetsuhisa, Hirose Tomoya, Kiguchi Takeyuki, Sado Junya, Kiyohara Kosuke, Takahashi Hiroki, Adachi Shingo, Noda Tomohiro, Izawa Junichi, Ohnishi Mitsuo, Shimazu Takeshi

机构信息

Department of Traumatology and Acute Critical Medicine Osaka University Graduate School of Medicine Suita Japan.

Department of Emergency Medicine Kyoto Prefectural University of Medicine Kyoto Japan.

出版信息

Acute Med Surg. 2019 Aug 22;7(1):e452. doi: 10.1002/ams2.452. eCollection 2020 Jan-Dec.

Abstract

AIM

Little is known about the detailed characteristics of patients using gas substances for self-inflicted injury in prehospital settings. The aim of this study was to investigate the characteristics, incidence trends, and outcomes of patients who used gas substances for self-inflicted injury in Osaka City, Japan, using ambulance records.

METHODS

This was a retrospective observational study that used data from 2009 to 2015. We extracted details from ambulance records of self-inflicted injury patients who used gas substances. The annual incidence of self-inflicted injury by gas substance and age group and Poisson regression models were applied for calculating the annual incidence trend by type of gas substance. The main outcome was confirmed death at the scene, and we also calculated the crude odds ratios and 95% confidence intervals for each gas substance.

RESULTS

During the study period, there were 324 self-inflicted injury patients who used gas substances. The most commonly used gases were carbon monoxide (CO) (54.9%), followed by hydrogen sulfide (12.7%), helium (6.5%). The incidence of CO and hydrogen sulfide have subsequently decreased ( for trend = 0.023 and <0.001, respectively); however, the incidence of helium did not change during the study period ( for trend = 0.586). The mortality rate was highest in patients who used helium (66.7% [14/21]) and the crude odds ratio of helium was 3.857 (95% confidence interval, 1.267-11.745;  = 0.017) compared with hydrogen sulfide.

CONCLUSION

This study revealed that the incidence of self-inflicted injury with helium did not change and its proportion of death at the scene was high in Osaka City.

摘要

目的

在院前环境中,对于使用气体物质进行自我伤害的患者的详细特征知之甚少。本研究的目的是利用救护车记录,调查日本大阪市使用气体物质进行自我伤害的患者的特征、发病趋势及结局。

方法

这是一项回顾性观察研究,使用了2009年至2015年的数据。我们从使用气体物质的自我伤害患者的救护车记录中提取详细信息。应用气体物质自我伤害的年发病率、年龄组及泊松回归模型来计算每种气体物质的年发病趋势。主要结局是在现场确认死亡,我们还计算了每种气体物质的粗比值比及95%置信区间。

结果

在研究期间,有324例使用气体物质进行自我伤害的患者。最常用的气体是一氧化碳(CO)(54.9%),其次是硫化氢(12.7%)、氦气(6.5%)。随后,CO和硫化氢的发病率有所下降(趋势检验P值分别为0.023和<0.001);然而,在研究期间氦气的发病率没有变化(趋势检验P值为0.586)。使用氦气的患者死亡率最高(66.7%[14/21]),与硫化氢相比,氦气的粗比值比为3.857(95%置信区间为1.267 - 11.745;P = 0.017)。

结论

本研究表明,在大阪市,使用氦气进行自我伤害的发病率没有变化,且其现场死亡率较高。

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