Drug Utilisation and Discovery Research Group, Faculty of Pharmacy, University of Jember, Jember, Jawa Timur 68121, Indonesia.
Centre for Biodiscovery and Molecular Development of Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, QLD 4878, Australia.
Biomolecules. 2020 Jan 24;10(2):181. doi: 10.3390/biom10020181.
This is an extensive review on epiphytic plants that have been used traditionally as medicines. It provides information on 185 epiphytes and their traditional medicinal uses, regions where Indigenous people use the plants, parts of the plants used as medicines and their preparation, and their reported phytochemical properties and pharmacological properties aligned with their traditional uses. These epiphytic medicinal plants are able to produce a range of secondary metabolites, including alkaloids, and a total of 842 phytochemicals have been identified to date. As many as 71 epiphytic medicinal plants were studied for their biological activities, showing promising pharmacological activities, including as anti-inflammatory, antimicrobial, and anticancer agents. There are several species that were not investigated for their activities and are worthy of exploration. These epipythes have the potential to furnish drug lead compounds, especially for treating cancers, and thus warrant indepth investigations.
这是一篇关于传统药用附生植物的综述。它提供了 185 种附生植物及其传统药用用途、原住民使用这些植物的地区、作为药物使用的植物部位及其制备方法,以及与其传统用途相一致的已报道的植物化学和药理学特性。这些药用附生植物能够产生多种次生代谢产物,包括生物碱,迄今为止已鉴定出 842 种植物化学物质。多达 71 种药用附生植物的生物活性已得到研究,表现出有前景的药理学活性,包括抗炎、抗菌和抗癌作用。有几种药用附生植物尚未进行活性研究,值得进一步探索。这些附生植物有可能提供药物先导化合物,特别是用于治疗癌症,因此需要深入研究。