Huh Eric H, Yi Paul H, Ray David M, Hsu Lawrence C H, Hui Ferdinand K, Khan Majid
Johns Hopkins Hospital, United States.
Johns Hopkins Hospital, United States.
J Clin Neurosci. 2020 Mar;73:125-129. doi: 10.1016/j.jocn.2020.01.004. Epub 2020 Jan 25.
Bone biopsies are traditionally performed using manual drill devices. More recently, powered drill biopsy systems have been developed, ostensibly to improve diagnostic yield. We compare the powered drill biopsy system to traditional manual needle devices on the basis of diagnostic yield, specimen size and material costs. 309 consecutive bone biopsy procedures performed with imaging guidance from a single academic institution were retrospectively reviewed. Specimen diagnostic adequacy, qualitative interpretation of diagnostically inadequate specimens, aggregate specimen volume and material costs were assessed. Econometric analysis was performed to assess the relationship between materials cost and diagnostic yield. Diagnostic yield and average core specimen volume were significantly higher in the powered drill group, with 86% of cases yielding adequate biopsy specimens versus 67% of cases using the manual method. The materials cost associated with the powered drill device was higher than those of any of the manual needle devices with an average difference of $270.19 per case, however, this was offset due to higher diagnostic yield suggesting that the increased diagnostic accuracy achieved by the powered drill does not carry a significant added financial burden. The powered drill bone biopsy system results in a significantly higher yield of diagnostically adequate biopsy specimens compared to traditional manual needles, possibly attributed to larger and more intact obtained core specimen volumes and is more economically viable off-setting the higher cost.
传统上,骨活检是使用手动钻孔设备进行的。最近,电动钻孔活检系统已经开发出来,表面上是为了提高诊断率。我们基于诊断率、样本大小和材料成本,将电动钻孔活检系统与传统手动穿刺针设备进行比较。回顾性分析了一家学术机构在影像引导下连续进行的309例骨活检手术。评估样本诊断的充分性、对诊断不充分样本的定性解读、样本总体积和材料成本。进行计量经济学分析以评估材料成本与诊断率之间的关系。电动钻孔组的诊断率和平均核心样本体积显著更高,电动钻孔组86%的病例获得了足够的活检样本,而使用手动方法的病例为67%。与电动钻孔设备相关的材料成本高于任何一种手动穿刺针设备,平均每例相差270.19美元,然而,由于诊断率更高,这一差异得到了抵消,这表明电动钻孔提高的诊断准确性不会带来显著的额外经济负担。与传统手动穿刺针相比,电动钻孔骨活检系统获得诊断充分的活检样本的比率显著更高,这可能归因于获取的核心样本体积更大且更完整,并且在经济上更可行,抵消了更高的成本。