Belfeki N, Gharbi E, Flateau C, Diamantis S
Department of Internal Medicine, Groupe Hospitalier Sud Ile de France, Melun.
Reumatismo. 2020 Jan 28;71(4):226-229. doi: 10.4081/reumatismo.2019.1252.
Wells' syndrome, also called eosinophilic cellulitis, is a rare eosinophilic dermatosis characterized by an unspecific inflammatory erythematous eruption often associated with systemic symptoms. Here we report the case of a 57-year-old female with bilateral painful pitting and pruritic feet progressive for two weeks despite one week of oral antibiotics. Skin biopsy was performed showing dermal eosinophilic infiltration. The patient showed a spontaneous progressive improvement of the condition. The presented case demonstrates both clinical and histologic presence of lesions of Wells' syndrome in the course of the disease. A careful diagnostic approach is needed because of the lack of specific signs. The global outcome is favorable and spontaneous resolution is possible.
韦尔斯综合征,又称嗜酸性粒细胞性蜂窝织炎,是一种罕见的嗜酸性粒细胞性皮肤病,其特征为常伴有全身症状的非特异性炎症性红斑疹。在此,我们报告一例57岁女性病例,其双足出现疼痛性凹陷和瘙痒,尽管口服抗生素一周,但仍持续进展两周。进行了皮肤活检,显示真皮嗜酸性粒细胞浸润。患者病情呈自发进行性改善。该病例展示了韦尔斯综合征在疾病过程中的临床和组织学病变表现。由于缺乏特异性体征,需要采取谨慎的诊断方法。总体预后良好,有可能自发缓解。