Allergy Unit, Département de Pneumologie et Addictologie, Hôpital Arnaud de Villeneuve, CHU de Montpellier, Univ Montpellier, Montpellier, France.
Pediatric Unit of the University Hospital of Pavia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Pediatr Allergy Immunol. 2020 Feb;31 Suppl 24:43-45. doi: 10.1111/pai.13151.
Corticosteroids (CS) are among the most prescribed drugs in pediatrics. In allergy, CS are prescribed for several different conditions. If CS show clear benefits when adequately prescribed, CS are also associated with several side effects, well known by pediatricians. As for asthma exacerbations, the oral route is always the preferred one in pediatrics. Several authors debated if the use of a single dose of dexamethasone is better in terms of efficacy, compared with a 3- to 5-day course of prednisone or prednisolone. Another interesting issue that has not been fully clarified concerns whether oral corticosteroids should be prescribed in preschoolers presenting with acute wheezing. The present review aims to review the most recent publications on this topic and to try to clarify which may be the best option in children suffering from asthma exacerbations.
皮质类固醇（CS）是儿科最常开的药物之一。在过敏方面，CS 被用于多种不同的疾病。如果 CS 在适当使用时显示出明显的益处，那么 CS 也与儿科医生熟知的几种副作用有关。对于哮喘恶化，口服途径始终是儿科的首选途径。一些作者就单剂量地塞米松在疗效方面是否优于泼尼松龙或泼尼松的 3-5 天疗程进行了辩论。另一个尚未完全阐明的有趣问题是，对于出现急性喘息的学龄前儿童，是否应开口服皮质类固醇。本综述旨在回顾关于这一主题的最新出版物，并试图阐明在患有哮喘恶化的儿童中哪种是最佳选择。
