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relocation pharyngoplasty 改善阻塞性睡眠呼吸暂停患者咽后周径狭窄的临床疗效。

The clinical efficacy of relocation pharyngoplasty to improve retropalatal circumferential narrowing in obstructive sleep apnea patients.

机构信息

Department of Otorhinolaryngology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea.

出版信息

Sci Rep. 2020 Feb 7;10(1):2101. doi: 10.1038/s41598-020-58920-9.

Abstract

Lateral pharyngeal wall appears to be a critical culprit of obstructive sleep apnea (OSA) subjects and relocation pharyngoplasty has been expected to be a promising surgical option to correct retropalatal circumferential narrowing in OSA patients. The purpose of our study is to evaluate the therapeutic outcomes of relocation pharyngoplasty and its clinical effectiveness in OSA patients with retropalatal circumferential narrowing. We performed relocation pharyngoplasty combined with nasal surgery in 133 OSA patients with the following characteristics: apnea-hypopnea index (AHI) over 10, retropalatal circumferential narrowing greater than grade I when awake, and redundant soft tissue around the lateral pharyngeal wall. The analysis of surgical success rate was performed with the data of 68 subjects who underwent pre and postoperative polysomnography. The objective success rate of relocation pharyngoplasty was 52.9%, and significant reduction of mean AHI with improvement of lowest SpO2 was seen in 69% of patients 3 months after the surgery. The median AHI was decreased from preoperative 37.3 to postoperative 21.4. Median lowest SpO2 changed from 78.4 to 84.1%. Total sleep time, daytime sleepiness, and visual analogue scale for snoring showed improvement as well. Postoperative complications including pain or bleeding were minimal in 133 subjects and a few patients complained of subtle taste loss. Our data demonstrate that relocation pharyngoplasty can be a favorable surgical option fighting against retropalatal circumferential narrowing.

摘要

咽侧壁似乎是阻塞性睡眠呼吸暂停(OSA)患者的关键罪魁祸首,移位咽成形术有望成为纠正 OSA 患者咽后环状狭窄的一种有前途的手术选择。我们的研究目的是评估移位咽成形术的治疗效果及其在咽后环状狭窄的 OSA 患者中的临床疗效。我们对 133 例 OSA 患者进行了移位咽成形术联合鼻手术,这些患者具有以下特征:呼吸暂停-低通气指数(AHI)大于 10,清醒时咽后环状狭窄大于 I 级,以及咽侧壁周围有多余的软组织。我们对 68 例接受术前和术后多导睡眠图检查的患者进行了手术成功率分析。移位咽成形术的客观成功率为 52.9%,69%的患者术后 3 个月 AHI 均值显著降低,最低 SpO2 改善。中位 AHI 从术前的 37.3 降至术后的 21.4。中位最低 SpO2 从 78.4 变为 84.1。总的睡眠时间、白天嗜睡和打鼾的视觉模拟评分也有所改善。133 例患者中,术后并发症包括疼痛或出血很少见,少数患者抱怨味觉轻微丧失。我们的数据表明,移位咽成形术可以作为对抗咽后环状狭窄的一种有利的手术选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8118/7005705/3f4b5f5c8846/41598_2020_58920_Fig1_HTML.jpg

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