Sugarbaker Paul H, Ben-Yaacov Almog, Hazzan David, Nissan Aviram
Program in Peritoneal Surface Malignancies, MedStar Washington Hospital Center, Washington, DC, USA.
Department of General and Oncological Surgery - Surgery C, The Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.
Int J Surg Case Rep. 2020;67:76-79. doi: 10.1016/j.ijscr.2020.01.022. Epub 2020 Jan 26.
Although uncommon, neoplasms of the appendix do exist. The two most common types are neuroendocrine tumors and mucinous appendiceal neoplasms.
In two patients unusual gross and microscopic findings in an appendectomy specimen were recorded. Special immunocytochemistry studies were used to determine the histologic type of the tumors in the appendix.
The clinical features and histopathology of two patients who had both a neuroendocrine tumor and a low grade appendiceal mucinous neoplasm in the same appendectomy specimen were described. Possibilities for the causation and treatment of this unusual condition were discussed. The incidence of this double malignancy was estimated at 2.5 in 1000 appendectomy specimens.
Although extremely unusual, a neuroendocrine tumor and a mucinous appendiceal neoplasm can exist in the same appendix. This condition is reported in two young patients.
阑尾肿瘤虽不常见，但确实存在。最常见的两种类型是神经内分泌肿瘤和阑尾黏液性肿瘤。
记录了两例阑尾切除标本中不寻常的大体和显微镜下表现。采用特殊免疫细胞化学研究来确定阑尾肿瘤的组织学类型。
描述了两名患者的临床特征和组织病理学情况，这两名患者在同一阑尾切除标本中既有神经内分泌肿瘤又有低级别阑尾黏液性肿瘤。讨论了这种不寻常情况的病因及治疗可能性。估计这种双重恶性肿瘤在每1000例阑尾切除标本中的发生率为2.5。
尽管极为罕见，但神经内分泌肿瘤和阑尾黏液性肿瘤可存在于同一阑尾中。本文报道了两名年轻患者的这种情况。
