College of Medicine, University of Arizona, 1501 North Campbell Ave, Tucson, AZ 85719, United States.
Department of Family & Community Medicine, College of Medicine, University of Arizona, 3950 South Country Club Drive, Suite 330, Tucson, AZ 85714, United States.
Addict Behav. 2020 Jun;105:106323. doi: 10.1016/j.addbeh.2020.106323. Epub 2020 Jan 20.
Over the past decade, opioid use disorder (OUD) among pregnant women has increased by over 400%. Although medication assisted treatment (MAT) provides necessary care for women with OUD, effective adjunctive nonpharmacological treatments have not been systematically identified. This is especially concerning for the postpartum period, which includes several unique risk factors (e.g., sleep deprivation, mood disturbances) for MAT non-adherence and relapse. This review summarizes the existing knowledge regarding nonpharmacological treatments for OUD during the postpartum period, as well as provides recommendations for the future.
PubMed and PsycINFO were searched in July 2018 using combinations of 28 keywords. Eligibility criteria included: (1) coverage of postpartum period, (2) use of nonpharmacological treatment for OUD, (3) conducted in clinical samples, and (4) written in English.
A total of 4 out of 38 identified articles met eligibility criteria. Two of the studies offered weekly on-site group counseling, with one also offering monthly social worker meetings. The third study offered four sessions with a patient navigator during the postpartum period. The last offered an employment intervention. All four reported favorable effects on OUD at end of follow-up (range: 30 days postpartum to 1 year postpartum). However, the details of the interventions, methodologies, and abstinence rates were sparse.
Few published studies examine nonpharmacological OUD treatments specific to the postpartum period. Identification of adjunctive nonpharmacological treatments designed to the unique needs of postpartum women is of critical public health importance, and further research is needed.
在过去的十年中,孕妇阿片类药物使用障碍(OUD)增加了 400%以上。虽然药物辅助治疗(MAT)为 OUD 女性提供了必要的护理,但尚未系统地确定有效的辅助非药物治疗方法。这对于产后时期尤其令人担忧,因为产后时期存在一些独特的 MAT 不依从和复发风险因素(例如,睡眠剥夺,情绪障碍)。这篇综述总结了有关产后 OUD 非药物治疗的现有知识,并为未来提供了建议。
2018 年 7 月,使用 28 个关键词的组合在 PubMed 和 PsycINFO 上进行了搜索。入选标准包括:(1)涵盖产后时期,(2)使用非药物治疗 OUD,(3)在临床样本中进行,以及(4)用英文书写。
在 38 篇已确定的文章中,有 4 篇符合入选标准。其中两项研究提供了每周一次的现场小组咨询,其中一项还提供了每月一次的社工会议。第三项研究在产后期间提供了四次与患者导航员的会议。最后一项提供了就业干预措施。所有四项研究都报告了在随访结束时 OUD 的良好效果(范围:产后 30 天至 1 年)。但是,干预措施的细节,方法和禁欲率却很少。
很少有已发表的研究专门针对产后时期的非药物性 OUD 治疗方法。确定旨在满足产后妇女独特需求的辅助性非药物治疗方法对于公共卫生至关重要,因此需要进一步研究。