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通过锝-甲氧基异丁基异腈单光子发射计算机断层显像/计算机断层扫描(Tc-MIBI SPECT/CT)检测到的2型甲状旁腺瘤病

Parathyromatosis type 2 detected by Tc-MIBI SPECT/CT.

作者信息

Cao Huixiao, Zeng Ming, Fang Haisheng, Tang Lijun, Liu Wei

机构信息

Department of Nuclear Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.

Department of Nephrology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.

出版信息

Gland Surg. 2019 Dec;8(6):806-809. doi: 10.21037/gs.2019.11.13.

Abstract

Parathyromatosis, which is defined as multiple foci of benign hyperfunctioning parathyroid tissue in neck or mediastinum, is a rare but severe cause of persistent/recurrent renal hyperparathyroidism (rHPT) after parathyroidectomy (PTX). It is hard to detect and remove all the foci. We present a case of parathyromatosis in a haemodialysed patient, who had three PTXs for persistent/recurrent rHPT and was free of recurrence during 31-month follow-up after the third PTX. Tc-MIBI SPECT/CT scan prior to the third PTX located all the lesions. The presented case suggests that preoperative Tc-MIBI SPECT/CT is useful for successful surgical removal of parathyromatosis.

摘要

甲状旁腺瘤病被定义为颈部或纵隔内多个良性功能亢进甲状旁腺组织灶,是甲状旁腺切除术后(PTX)持续性/复发性肾性甲状旁腺功能亢进(rHPT)的一种罕见但严重的病因。很难检测并切除所有病灶。我们报告一例血液透析患者的甲状旁腺瘤病病例,该患者因持续性/复发性rHPT接受了三次PTX,第三次PTX后31个月的随访期间无复发。第三次PTX前的Tc-MIBI SPECT/CT扫描定位了所有病灶。该病例表明术前Tc-MIBI SPECT/CT有助于成功手术切除甲状旁腺瘤病。

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