Department of Neuroradiology, Ludwig Maximilian University, Munich, Germany.
Department of Neuroradiology, Bezirkskrankenhaus Gunzburg, Gunzburg, Germany.
Interv Neuroradiol. 2020 Aug;26(4):433-438. doi: 10.1177/1591019919900879. Epub 2020 Feb 11.
Casper-RX (MicroVention, Aliso Viejo, California, USA) is a dual-layer closed cell stent recently introduced as a carotid artery revascularization device. Although its effectiveness and safety has been proved in elective cases, there are contradictive results regarding its patency in emergency settings. The purpose of the study is to present our single-center experience with the Casper-RX stent in the emergency interventions.
Consecutive patients who underwent emergency carotid artery stenting using Casper-RX system with or without additional intracranial thrombectomy between August 2016 and June 2019 at our institution were included. Primary end point was the short-term patency of the carotid stents evaluated before hospital discharge by use of Doppler ultrasonography.
Twenty-nine procedures performed on 28 patients were included in the study. All stents were patent on final angiograms. Acute stent occlusion was observed only in one case (3.4%) with a spontaneous cervical internal carotid artery dissection the day after the procedure. In 26 (89.6%) cases, an additional intracranial thrombectomy was performed with a successful recanalization rate of 96.1%. Seven adverse events occurred peri-/post-procedural: two cases (6.9%) with iatrogenic dissection of distal cervical internal carotid artery during intracranial thrombectomy, two parenchymal hematoma type 2 (6.8%), and three patients (10.3%) developed massive infarction.
This study supports the safety and efficacy of the Casper-RX stent in emergency endovascular carotid artery revascularization procedures.
Casper-RX(美国加利福尼亚州亚利桑那州的 MicroVention)是一种双层闭孔细胞支架,最近被引入作为颈动脉血运重建装置。尽管其在择期病例中的有效性和安全性已得到证实,但在紧急情况下其通畅性的结果存在矛盾。本研究的目的是介绍我们使用 Casper-RX 支架进行的单一中心的紧急血管内干预经验。
连续 28 例患者在我们的机构中接受了使用 Casper-RX 系统进行的紧急颈动脉支架置入术,包括或不包括额外的颅内血栓切除术,该研究包括这些患者。主要终点是使用多普勒超声评估在出院前的颈动脉支架的短期通畅性。
在 2016 年 8 月至 2019 年 6 月期间,共进行了 29 例手术,所有支架在最终血管造影上均显示通畅。只有 1 例(3.4%)患者在手术后第二天出现自发性颈内动脉夹层,出现急性支架闭塞。在 26 例(89.6%)患者中,进行了额外的颅内血栓切除术,其再通率为 96.1%。7 例围手术期/术后发生不良事件:2 例(6.9%)患者在颅内血栓切除术中发生远端颈内动脉医源性夹层,2 例(6.8%)患者发生 2 型皮质下血肿,3 例(10.3%)患者发生大面积梗死。
本研究支持 Casper-RX 支架在紧急血管内颈动脉血运重建手术中的安全性和有效性。