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先天性巨结肠患儿经肛门拖出吻合术:术后结局的全国性分析

Pull-through procedure in children with Hirschsprung disease: A nationwide analysis on postoperative outcomes.

机构信息

Dewitt-Daughtry Family Department of Surgery, Division of Pediatric Surgery, University of Miami Miller School of Medicine, Miami, FL.

Dewitt-Daughtry Family Department of Surgery, Division of Trauma and Acute Care Surgery, University of Miami Miller School of Medicine, Miami, FL.

出版信息

J Pediatr Surg. 2020 May;55(5):899-903. doi: 10.1016/j.jpedsurg.2020.01.038. Epub 2020 Jan 31.

Abstract

PURPOSE

No nationwide studies on hospital readmissions exist for children who have undergone pull-through operations for Hirschsprung disease. The study aim is to identify determinants of postoperative discharge outcomes and hospital readmissions in children with Hirschsprung disease.

METHODS

The Nationwide Readmissions Database for 2010-2014 was queried for children (<18yo) with Hirschsprung disease and whom had undergone pull-through procedure, utilizing ICD-9 codes 751.3 and 48.40-69, respectively. Outcomes included complications and readmissions at 30-day and 1-year. Results were weighted for national estimates.

RESULTS

The cohort consisted of 3635 patients, 75% male and 79% < 1 year of age. Readmission rates at 30 days and 1-year were 20% and 36%, respectively. Overall, the most common diagnoses for readmission were gastrointestinal disorders (46%) and infections (39%). All age groups had a ≥ 10% readmission rate for gastrointestinal disorders. Infants were more likely to be admitted for enterocolitis and infections (16% and 15%), while children (1-6 years old) were most commonly readmitted for electrolyte disturbances (12%). Total hospitalization cost was over $162 million with $24 million from readmissions.

CONCLUSION

Pull-through procedure for Hirschsprung disease is associated with high readmissions and associated economic burden. Age specific interventions to prevent unnecessary readmissions could improve outcomes and curtail healthcare spending.

TYPE OF STUDY

Retrospective Comparative Analysis.

LEVEL OF EVIDENCE

Level III.

摘要

目的

目前尚无全国性研究针对接受巨结肠根治术的儿童的住院再入院情况。本研究旨在确定巨结肠患儿术后出院结局和再入院的决定因素。

方法

利用国际疾病分类第 9 版(ICD-9)编码 751.3 和 48.40-69,检索 2010-2014 年全国再入院数据库中接受巨结肠根治术的儿童(<18 岁)病例,分别分析术后 30 天和 1 年的并发症和再入院情况。结果进行全国估计加权。

结果

该队列共纳入 3635 例患者,75%为男性,79%年龄<1 岁。术后 30 天和 1 年的再入院率分别为 20%和 36%。总体而言,再入院最常见的诊断为胃肠道疾病(46%)和感染(39%)。所有年龄组的胃肠道疾病再入院率均≥10%。婴儿更易因肠炎和感染(16%和 15%)而入院,而儿童(1-6 岁)最常因电解质紊乱(12%)而再次入院。总住院费用超过 1.62 亿美元,其中 2400 万美元来自再入院。

结论

巨结肠根治术与较高的再入院率和相关经济负担相关。针对特定年龄的干预措施以预防不必要的再入院可改善结局并控制医疗保健支出。

研究类型

回顾性比较分析。

证据等级

III 级。

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