Harris College of Nursing and Health Sciences, Texas Christian University, Fort Worth, Texas.
University of Alabama at Birmingham, School of Nursing, Birmingham, Alabama.
J Spec Pediatr Nurs. 2020 Jul;25(3):e12288. doi: 10.1111/jspn.12288. Epub 2020 Feb 17.
Diagnosis and treatment for individuals with brain tumors during childhood involves sequelae, including abnormal weight gain. This symptom is commonly clustered with fatigue and increased risk for cardiovascular disease. Children's Oncology Group recommendations include annual surveillance of body mass index (BMI) and cardiometabolic comorbidities; however, there has been little emphasis on individualized screening early in survivorship.
The primary purpose of this paper is to describe the findings of abnormal weight gain and its correlates in a sample of young childhood brain tumor survivors during early survivorship.
This cross-sectional multi-site study included brain tumor survivors of ages 8-12 years who were less than 6 years posttreatment. Convenience sampling from two pediatric cancer centers in the southern United States was utilized. Data collected included BMI, parent report of sleep, and child report of fatigue and stress.
The sample (N = 21) consisted of children who had received chemotherapy, radiation treatment, and surgery for childhood brain tumor. BMI in overweight and obese categories exceeded normative samples with 38% at or above the 85th percentile. There were clinically significant relationships with fatigue, stress about weight, tumor location, cranial radiation, chemotherapy, and recurrence PRACTICE IMPLICATIONS: Screening for abnormal weight gain and related factors, such as fatigue should begin early in survivorship after childhood brain tumor treatment completion with the aim of health promotion and disease prevention. Adiposity measurement techniques should be utilized in future clinical and research settings to improve assessment of cardiometabolic risk.
儿童脑瘤患者的诊断和治疗会产生一些后遗症，包括体重异常增加。这种症状通常与疲劳和心血管疾病风险增加有关。儿童肿瘤学组的建议包括每年监测体重指数（BMI）和心脏代谢合并症；然而，在生存随访早期，对个体化筛查的重视程度较低。
本文的主要目的是描述在生存随访早期，对一组年轻的儿童脑肿瘤幸存者中异常体重增加及其相关因素的研究结果。
这是一项横断面多中心研究，纳入年龄在 8-12 岁、治疗后不到 6 年的脑肿瘤幸存者。研究在美国南部的两家儿科癌症中心进行便利抽样。收集的数据包括 BMI、父母报告的睡眠情况，以及儿童报告的疲劳和压力。
该样本（N=21）由接受过化疗、放疗和手术治疗的儿童脑肿瘤患者组成。超重和肥胖类别的 BMI 超过了正常样本，有 38%的人处于或高于第 85 百分位。疲劳、对体重的压力、肿瘤位置、颅部放疗、化疗和复发与 BMI 存在显著的临床相关性。
在儿童脑肿瘤治疗完成后的生存随访早期，应开始筛查异常体重增加及相关因素，如疲劳，以促进健康和预防疾病。在未来的临床和研究环境中，应采用体脂测量技术来提高对心脏代谢风险的评估。
