Department of Internal Medicine and Geriatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
Department of Internal Medicine and Geriatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
BMJ Open. 2020 Feb 18;10(2):e035012. doi: 10.1136/bmjopen-2019-035012.
Poor self-rated health (SRH) is a strong predictor of premature mortality in older adults. Trajectories of poor SRH are associated with multimorbidity and unhealthy behaviours. Whether trajectories of SRH are associated with deviating physiological markers is unclear. This study identified trajectories of SRH and investigated the associations of trajectory membership with chronic diseases, health risk behaviours and physiological markers in community-dwelling older adults.
Prospective general population cohort.
Trajectories of SRH over 5 years were identified using data of 11 600 participants aged 65 years and older of the Lifelines Cohort Study.
Trajectories of SRH were the main outcome. Covariates included demographics (age, gender, education), chronic diseases, health-risk behaviour (physical activity, smoking, drinking) and physiological markers (body mass index, cardiovascular function, lung function, glucose metabolism, haematological condition, endocrine function, renal function, liver function and cognitive function).
Four stable trajectories were identified, including excellent (n=607, 6%), good (n=2111, 19%), moderate (n=7677, 65%) and poor SRH (n=1205, 10%). Being women (OR: 1.4; 95% CI: 1.0 to 1.9), low education (OR: 2.1; 95% CI: 1.5 to 3.0), one (OR: 10.4; 95% CI: 7.4 to 14.7) or multiple chronic diseases (OR: 37.8; 95% CI: 22.4 to 71.8), smoking (OR: 1.8; 95% CI: 1.0 to 3.2), physical inactivity (OR: 3.1; 95% CI: 1.8 to 5.2), alcohol abstinence (OR: 2.2; 95% CI: 1.4 to 3.2) and deviating physiological markers (OR: 1.5; 95% CI: 1.1 to 2.0) increase the odds for a higher probability of poor SRH trajectory membership compared with excellent SRH trajectory membership.
SRH of community-dwelling older adults is stable over time with the majority (65%) having moderate SRH. Older adults with higher probabilities of poor SRH often have unfavourable health status.
自我报告健康状况较差(SRH)是老年人过早死亡的强有力预测因素。较差 SRH 的轨迹与多种疾病和不健康行为有关。SRH 轨迹是否与偏离的生理指标有关尚不清楚。本研究确定了 SRH 轨迹,并调查了轨迹成员与社区居住的老年人的慢性病、健康风险行为和生理指标之间的关联。
前瞻性一般人群队列。
使用莱夫林斯队列研究中 11600 名 65 岁及以上参与者的数据,确定了 5 年内 SRH 的轨迹。
SRH 轨迹是主要结果。协变量包括人口统计学因素(年龄、性别、教育)、慢性病、健康风险行为(体力活动、吸烟、饮酒)和生理指标(体重指数、心血管功能、肺功能、葡萄糖代谢、血液状况、内分泌功能、肾功能、肝功能和认知功能)。
确定了四个稳定的轨迹,包括优秀(n=607,6%)、良好(n=2111,19%)、中等(n=7677,65%)和较差 SRH(n=1205,10%)。女性(OR:1.4;95%CI:1.0 至 1.9)、低教育(OR:2.1;95%CI:1.5 至 3.0)、一种(OR:10.4;95%CI:7.4 至 14.7)或多种慢性疾病(OR:37.8;95%CI:22.4 至 71.8)、吸烟(OR:1.8;95%CI:1.0 至 3.2)、身体活动不足(OR:3.1;95%CI:1.8 至 5.2)、戒酒(OR:2.2;95%CI:1.4 至 3.2)和生理指标偏离(OR:1.5;95%CI:1.1 至 2.0)的老年人,与优秀 SRH 轨迹成员相比,较差 SRH 轨迹成员的可能性更高。
社区居住的老年人的 SRH 随时间相对稳定,大多数(65%)的老年人的 SRH 为中等水平。较差 SRH 的老年人通常健康状况较差。