Grupo de Física Nuclear and IPARCOS, Univ. Complutense de Madrid, CEI Moncloa, Spain; Université de Paris, PARCC, INSERM, F-75015 Paris, France.
Grupo de Física Nuclear and IPARCOS, Univ. Complutense de Madrid, CEI Moncloa, Spain; Instituto de Investigación Biomédica, Hospital General Universitario Carlos III, Madrid, Spain.
Ultrasonics. 2020 Apr;103:106097. doi: 10.1016/j.ultras.2020.106097. Epub 2020 Feb 3.
Speed of Sound (SoS) maps from ultrasound tomography (UST) provide valuable quantitative information for soft tissue characterization and identification of lesions, making this technique interesting for breast cancer detection. However, due to the complexity of the processes that characterize the interaction of ultrasonic waves with matter, classic and fast tomographic algorithms such as back-projection are not suitable. Consequently, the image reconstruction process in UST is generally slow compared to other more conventional medical tomography modalities. With the aim of facilitating the translation of this technique into real clinical practice, several reconstruction algorithms are being proposed to make image reconstruction in UST to be a fast and accurate process. The geometrical acoustic approximation is often used to reconstruct SoS with less computational burden in comparison with full-wave inversion methods. In this work, we propose a simple formulation to perform on-the-flight reconstruction for UST using geometrical acoustics with refraction correction based on quadratic Bézier polynomials. Here we demonstrate that the trajectories created with these polynomials are an accurate approximation to reproduce the refracted acoustic paths connecting the emitter and receiver transducers. The method is faster than typical acquisition times in UST. Thus, it can be considered a step towards real-time reconstructions, which may contribute to its future clinical translation.
超声层析成像(UST)的声速(SoS)图为软组织特征分析和病变识别提供了有价值的定量信息,这使得该技术在乳腺癌检测中具有很大的吸引力。然而,由于超声与物质相互作用的过程十分复杂,经典的快速层析算法,如反向投影法,并不适用。因此,与其他更传统的医学层析成像模式相比,UST 的图像重建过程通常较慢。为了便于将该技术转化为实际的临床实践,人们提出了几种重建算法,以实现 UST 中快速而准确的图像重建。与全波反演方法相比,几何声学近似法在计算负担方面具有优势,常用于重建 SoS。在这项工作中,我们提出了一种简单的基于二次贝塞尔多项式的折射校正几何声学在线重建 UST 的方法。我们证明了这些多项式创建的轨迹可以准确地再现连接发射器和接收器换能器的折射声路径。该方法比 UST 中的典型采集时间更快。因此,它可以被视为实时重建的一个步骤,这可能有助于其未来的临床转化。