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老年人群中从冠状静脉系统消融的室性心律失常/室性早搏的独特特征。

Unique features of epicardial ventricular arrhythmias/premature ventricular complexes ablated from coronary venous system in veteran population.

作者信息

Mar Philip L, Barmeda Mamta, Stucky Marcelle A, Devabahktuni Subodh R, Garlie Jason, Miller John M, Jain Rahul

机构信息

Department of Cardiology, Indiana University School of Medicine, Indianapolis, IN, USA; Roudebush Veterans Affairs Medical Center, Indianapolis, IN, USA.

Roudebush Veterans Affairs Medical Center, Indianapolis, IN, USA; Indiana University Health, Indianapolis, IN, USA.

出版信息

Indian Pacing Electrophysiol J. 2020 May-Jun;20(3):97-104. doi: 10.1016/j.ipej.2020.02.001. Epub 2020 Feb 18.

Abstract

INTRODUCTION

Ventricular arrhythmias/premature ventricular complexes (VA/PVCs) that can be ablated from within the coronary venous system (CVS) have not been described in the United States Veterans Health Administration (VHA) population. We retrospectively studied the VA/PVCs ablations that were performed in the VHA population.

METHODS

Data from 42 consecutive patients who underwent VA/PVCs ablation at Veterans Affairs Hospital, Indianapolis, IN, with 44 VA/PVCs was included in the study. Patients were divided into two groups (CVS group [n = 10], and non-CVS group [n = 32]) based on where the earliest pre-systolic activation was seen with >95% pacematch.

RESULTS

The mean age in CVS group was 65 ± 8 years versus 64 ± 12 years (p = 0.69) in non-CVS group. Overall there was a statistically significant reduction in PVC burden post ablation (27.7% (pre-ablation) versus 4.7% (post-ablation). In the 10 patients in the CVS group, either ablation or catheter-related mechanical trauma resulted in complete (n = 6 [60%]) or partial (n = 4 [40%]) long-term suppression of VA/PVCs. Right bundle branch block-type VA/PVC (9/11: 82%) was the most common morphology in the CVS group, whereas in the non-CVS group, this type was seen in only 3/33 (9%). The CVS group (25% of total VA/PVCs) had shorter activation time compared to non CVS group.

CONCLUSION

In our experience VA/PVCs with electrocardiograms suggestive of epicardial origin can often be safely and successfully ablated within the coronary venous system. These arrhythmias have unique features in Veterans patient population.

摘要

引言

在美国退伍军人健康管理局(VHA)人群中,尚未有关于可从冠状静脉系统(CVS)内进行消融的室性心律失常/室性早搏(VA/PVCs)的描述。我们回顾性研究了在VHA人群中进行的VA/PVCs消融术。

方法

本研究纳入了42例在印第安纳州印第安纳波利斯退伍军人事务医院接受VA/PVCs消融术的连续患者,共44处VA/PVCs。根据最早的收缩前期激动在何处出现且起搏匹配度>95%,将患者分为两组(CVS组[n = 10]和非CVS组[n = 32])。

结果

CVS组的平均年龄为65±8岁,而非CVS组为64±12岁(p = 0.69)。总体而言,消融术后PVC负荷有统计学意义的显著降低(消融前为27.7%,消融后为4.7%)。在CVS组的10例患者中,消融或导管相关的机械损伤导致VA/PVCs完全(n = 6 [60%])或部分(n = 4 [40%])长期抑制。右束支阻滞型VA/PVC(9/11:82%)是CVS组中最常见的形态,而在非CVS组中,仅3/33(9%)可见此类型。与非CVS组相比,CVS组(占总VA/PVCs的25%)的激动时间更短。

结论

根据我们的经验,心电图提示起源于心肌外膜的VA/PVCs通常可在冠状静脉系统内安全、成功地进行消融。这些心律失常在退伍军人患者群体中有独特特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f95d/7244881/6ffbba3e223c/gr1.jpg

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