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植入式心脏电子设备相关心内膜炎中的三尖瓣手术:修复还是置换?

Tricuspid valve surgery in implantable cardiac electronic device-related endocarditis: Repair or replace?

作者信息

Çakıcı Mehmet, Özçınar Evren, Baran Çağdaş, Gümüş Fatih, Durdu Mustafa Serkan, İnan Mustafa Bahadır, Eryılmaz Sadık, Akar Ahmet Rüçhan

机构信息

Department of Cardiovascular Surgery, Medical Faculty of Ankara University, Ankara, Turkey.

出版信息

Turk Gogus Kalp Damar Cerrahisi Derg. 2018 Apr 30;26(2):183-191. doi: 10.5606/tgkdc.dergisi.2018.14790. eCollection 2018 Apr.

Abstract

BACKGROUND

The aim of this study was to investigate lead endocarditis-related tricuspid valve regurgitation, to identify underlying causes, and to report our surgical approaches to tricuspid valve endocarditis.

METHODS

Between March 2010 and August 2016, medical records of a total of 43 patients (23 males, 20 females; mean age: 63.2±13.6 years; range 48 to 72 years) who underwent tricuspid valve surgery for severe tricuspid regurgitation caused by lead endocarditis, which was previously placed as an implantable cardiac electronic device were reviewed. We removed all systems including infected leads and generators, revised infected wounds and tissues, performed tricuspid valve surgery for lead endocarditis, and applied long-term intravenous antibiotic regimen for the culprit agent, as confirmed by the culture.

RESULTS

Of 43 patients, 18 underwent tricuspid valve repair and 25 underwent tricuspid valve replacement for lead endocarditisrelated severe tricuspid valve regurgitation. During followup (range, 2 to 62 months), two patients required temporary mechanical support due to postoperative acute right heart failure, while eight patients died due to sepsis (n=6; 14%) and stroke (n=2; 4.6%) in the early postoperative period. The remaining patients showed significant improvement in signs and symptoms of heart failure.

CONCLUSION

Our study results suggest that incompetent experience and inaccurate decision for valve repair may result in delayed valve replacement and prolonged operation time.

摘要

背景

本研究旨在调查导线相关性心内膜炎所致的三尖瓣反流,确定潜在病因,并报告我们针对三尖瓣心内膜炎的手术方法。

方法

回顾2010年3月至2016年8月期间共43例患者(23例男性,20例女性;平均年龄:63.2±13.6岁;范围48至72岁)的病历,这些患者因先前作为植入式心脏电子设备植入的导线相关性心内膜炎导致严重三尖瓣反流而接受了三尖瓣手术。我们移除了所有系统,包括感染的导线和发生器,修复了感染的伤口和组织,对导线相关性心内膜炎进行了三尖瓣手术,并根据培养结果对致病菌应用了长期静脉抗生素治疗方案。

结果

43例患者中,18例因导线相关性心内膜炎所致严重三尖瓣反流接受了三尖瓣修复,25例接受了三尖瓣置换。在随访期间(范围2至62个月),2例患者因术后急性右心衰竭需要临时机械支持,而8例患者在术后早期因败血症(n = 6;14%)和中风(n = 2;4.6%)死亡。其余患者心力衰竭的体征和症状有显著改善。

结论

我们的研究结果表明,瓣膜修复经验不足和决策不准确可能导致瓣膜置换延迟和手术时间延长。

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本文引用的文献

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Outcomes of tricuspid valve repair and replacement: a propensity analysis.三尖瓣修复与置换的结果:一项倾向分析。
Ann Thorac Surg. 2009 Jan;87(1):83-8; discussion 88-9. doi: 10.1016/j.athoracsur.2008.10.003.
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Isolated tricuspid valve endocarditis.孤立性三尖瓣心内膜炎
Int J Infect Dis. 2009 May;13(3):e109-11. doi: 10.1016/j.ijid.2008.07.018. Epub 2008 Nov 4.

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