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慢性肠系膜缺血的人工血管搭桥术的治疗结果。

The outcomes of prosthetic bypass grafting for chronic mesenteric ischemia.

作者信息

Oğuz Emrah, Ertugay Serkan, Yusifov Rauf, Sahutoğlu Cengiz, Posacıoğlu Hakan

机构信息

Department of Cardiovascular Surgery, Medicine Faculty of Ege University, İzmir, Turkey.

Department of Anesthesiology and Reanimation, Medicine Faculty of Ege University, İzmir, Turkey.

出版信息

Turk Gogus Kalp Damar Cerrahisi Derg. 2018 Apr 30;26(2):223-228. doi: 10.5606/tgkdc.dergisi.2018.15361. eCollection 2018 Apr.

Abstract

BACKGROUND

This study aims to analyze early and late outcomes of the prosthetic bypass grafting procedure in the treatment of chronic mesenteric ischemia.

METHODS

Twenty-two patients (15 males, 7 females; mean age 60±10 years; range, 32 to 78 years) who underwent prosthetic bypass grafting for chronic mesenteric ischemia due to atherosclerosis between March 2009 and March 2017 were included in this study. The demographic and operative data were analyzed retrospectively.

RESULTS

The most common risk factors for atherosclerosis were hypertension, diabetes, and hyperlipidemia. A total of 72% of the patients were active tobacco users. The common symptoms were postprandial angina and weight loss. Six patients (27%) had a history of endovascular intervention for mesenteric revascularization. Celiac artery bypass grafting was performed in 17 patients, while superior mesenteric artery bypass grafting was performed in 21 patients. Retrograde bypass was done in all patients and polytetrafluoroethylene grafts were used in 20 patients (90%). The mean hospital stay was 10.5 days and the mean follow-up was 44.7 months. The most common postoperative complications were respiratory failure (9%) and infection (9%). In-hospital mortality was observed in one patient (%4.5)who had acute myocardial infarction-related low cardiac output. One patient had graft thrombosis resulting in early graft infection a month after discharge. Late graft thrombosis was observed in two patients at 44 and 85 months, respectively. Late mortality was observed in two patients due to malignancy and cerebral bleeding, respectively.

CONCLUSION

Prosthetic bypass grafting via open surgery for chronic mesenteric ischemia seems to be an effective treatment in long-term and can be implemented with low surgical risks.

摘要

背景

本研究旨在分析人工血管旁路移植术治疗慢性肠系膜缺血的早期和晚期疗效。

方法

纳入2009年3月至2017年3月期间因动脉粥样硬化性慢性肠系膜缺血接受人工血管旁路移植术的22例患者(15例男性,7例女性;平均年龄60±10岁;范围32至78岁)。对人口统计学和手术数据进行回顾性分析。

结果

动脉粥样硬化最常见的危险因素是高血压、糖尿病和高脂血症。共有72%的患者为现吸烟者。常见症状为餐后心绞痛和体重减轻。6例患者(27%)有肠系膜血管重建的血管内介入治疗史。17例患者行腹腔动脉旁路移植术,21例患者行肠系膜上动脉旁路移植术。所有患者均采用逆行旁路移植术,20例患者(90%)使用聚四氟乙烯移植物。平均住院时间为10.5天,平均随访时间为44.7个月。最常见的术后并发症是呼吸衰竭(9%)和感染(9%)。1例因急性心肌梗死导致心输出量降低的患者发生院内死亡(4.5%)。1例患者出院1个月后发生移植血管血栓形成,导致早期移植血管感染。分别在44个月和85个月时观察到2例患者发生晚期移植血管血栓形成。分别有2例患者因恶性肿瘤和脑出血导致晚期死亡。

结论

通过开放手术进行人工血管旁路移植术治疗慢性肠系膜缺血似乎是一种长期有效的治疗方法,且手术风险较低。

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