Rao K Raghavendra, Reddy S, Kashyap J R, Vikas K, Reddy Hithesh, Ramalingam Vadivelu
Department of Cardiology, Government Medical College and Hospital, Sector 32, Chandigarh 160030, India.
Department of Cardiology, Velammal Medical College Hospital and Research Institute, Madurai 625009, India.
Case Rep Cardiol. 2020 Feb 6;2020:9628719. doi: 10.1155/2020/9628719. eCollection 2020.
Very late stent thrombosis (VLST) is a catastrophic and life-threatening complication after percutaneous coronary intervention which presents as an acute coronary syndrome with significantly high mortality and morbidity. VLST is a rare entity with drug-eluting stents and even rarer with bare metal stents. The exact pathophysiologic mechanism of VLST after BMS implantation is not known although various mechanisms have been proposed. Recently, in-stent neoatherosclerosis with intimal plaque rupture has been proposed as a potential mechanism of VLST after BMS. We report a rare case of VLST occurring 17 years after BMS implantation with angiographic and intravascular imaging evidence which provides insight into the mechanisms of VLST.
极晚期支架内血栓形成(VLST)是经皮冠状动脉介入治疗后一种灾难性且危及生命的并发症,表现为急性冠状动脉综合征,死亡率和发病率显著升高。VLST在药物洗脱支架中较为罕见,在裸金属支架中更为罕见。尽管已经提出了各种机制,但BMS植入后VLST的确切病理生理机制尚不清楚。最近,有人提出支架内新生动脉粥样硬化伴内膜斑块破裂是BMS术后VLST的一种潜在机制。我们报告了1例BMS植入17年后发生VLST的罕见病例,有血管造影和血管内成像证据,这为VLST的机制提供了见解。