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注意缺陷多动障碍、冲动性、焦虑和抑郁症状在童年创伤与强迫症症状严重程度之间关系中的中介作用

Attention Deficit Hyperactivity Disorder, Impulsivity, Anxiety, and Depression Symptoms Mediating the Relationship Between Childhood Trauma and Symptoms Severity of Obsessive-Compulsive Disorder.

作者信息

Çoban Adnan, Tan Oğuz

机构信息

HTA Neuropsychiatry Center, İstanbul, Turkey.

NP Feneryolu Medical Center, Üsküdar University, İstanbul, Turkey.

出版信息

Noro Psikiyatr Ars. 2019 Aug 16;57(1):37-43. doi: 10.29399/npa.23654. eCollection 2020 Mar.

DOI:10.29399/npa.23654
PMID:32110149
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7024829/
Abstract

INTRODUCTION

A growing body of research associates childhood trauma with obsessive-compulsive disorder (OCD). The aim of this study was to investigate the relationships between childhood trauma and OCD, including both its severity and OCD patients' comorbid impulsivity, ADHD, anxiety, and depressive symptoms.

METHODS

A convenient sample consisting of 106 patients with OCD was given the Childhood Trauma Questionnaire (CTQ), Yale-Brown Obsessive Compulsive Scale (Y-BOCS), Wender Utah Rating Scale (WURS), Hamilton Rating Scale for Depression (HAM-D), Beck Anxiety Inventory (BAI), and Barratt Impulsivity Scale-11 (BIS-11).

RESULTS

The results showed that childhood trauma indirectly predicts the severity of OCD and directly predicts comorbidities in OCD patients, including anxiety, ADHD, WURS, and impulsivity. Patients with childhood trauma had higher WURS, BAI, and BIS-11 scores and fewer years of education. Ongoing adult ADHD was more common in individuals with childhood trauma.

CONCLUSION

A history of childhood trauma in OCD patients has indirect effects on the severity of OCD and depressive symptoms and is associated with more severe anxiety, higher levels of impulsivity, higher prevalence of ADHD, and lower levels of education. More research is needed to clarify the effects of childhood trauma on OCD severity and comorbidity.

摘要

引言

越来越多的研究将童年创伤与强迫症(OCD)联系起来。本研究的目的是调查童年创伤与强迫症之间的关系,包括其严重程度以及强迫症患者的共病冲动性、注意力缺陷多动障碍(ADHD)、焦虑和抑郁症状。

方法

对由106名强迫症患者组成的便利样本进行儿童创伤问卷(CTQ)、耶鲁-布朗强迫症量表(Y-BOCS)、温德尔犹他评定量表(WURS)、汉密尔顿抑郁评定量表(HAM-D)、贝克焦虑量表(BAI)和巴拉特冲动性量表-11(BIS-11)评估。

结果

结果表明,童年创伤间接预测强迫症的严重程度,并直接预测强迫症患者的共病情况,包括焦虑、ADHD、WURS和冲动性。有童年创伤的患者WURS、BAI和BIS-11得分更高,受教育年限更少。童年创伤患者中成人期持续性ADHD更为常见。

结论

强迫症患者的童年创伤史对强迫症的严重程度和抑郁症状有间接影响,并与更严重的焦虑、更高水平的冲动性、更高的ADHD患病率和更低的受教育水平相关。需要更多研究来阐明童年创伤对强迫症严重程度和共病的影响。

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