Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy; Anaesthesia and Intensive Care Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy; Anaesthesia and Intensive Care Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
J Cardiothorac Vasc Anesth. 2020 May;34(5):1263-1269. doi: 10.1053/j.jvca.2020.01.052. Epub 2020 Feb 1.
The echocardiographic indices have not been validated in critically ill population. The authors investigated the correlation between some echocardiographic and hemodynamic parameters.
Prospective, spontaneous, noninterventional observational study.
Adult cardiothoracic intensive care unit, single center (Royal Brompton Hospital, London, United Kingdom).
Consecutive adult patients admitted to the cardiothoracic intensive care unit for severe respiratory failure, primary cardiocirculatory failure, and post-aortic surgery.
Clinical hemodynamic parameters (stroke volume [SV], cardiac output [CO], mean arterial pressure [MAP], and cardiac power index [CPI]) and echocardiographic indices of ventricular function (left ventricular total isovolumic time [t-IVT], mitral annular plane systolic excursion [MAPSE], and left ventricular fraction [LVEF]) were evaluated offline.
The study comprised 117 patients (age 57.2 ± 19; 60.6% male). The t-IVT showed an inverse correlation with SV, CO, MAP, and CPI (r -67%; -38%; -45%; -51%, respectively). MAPSE exhibited a positive correlation with SV, CO, MAP, and CPI (r 43%; 44%; 34%; 31%, respectively). LVEF did not show any correlation. In the multivariate analysis the association between t-IVT and hemodynamics was confirmed for SV, CO, MAP, and CPI, with the highest partial correlation between t-IVT and MAP (R = -58%).
MAPSE and t-IVT are 2 reproducible and reliable echocardiographic indices of systolic function and ventricular efficacy associated with hemodynamic variables in cardiothoracic critically ill patients, whereas LVEF did not show any correlation.
超声心动图指标尚未在危重病患者中得到验证。作者研究了一些超声心动图和血流动力学参数之间的相关性。
前瞻性、自发性、非干预性观察研究。
成人心胸重症监护病房,单中心(英国伦敦皇家 Brompton 医院)。
连续收治的因严重呼吸衰竭、原发性心循环衰竭和主动脉手术后入住心胸重症监护病房的成年患者。
临床血流动力学参数(每搏量 [SV]、心输出量 [CO]、平均动脉压 [MAP]和心脏功率指数 [CPI])和心室功能的超声心动图指数(左心室总等容时间 [t-IVT]、二尖瓣环平面收缩期位移 [MAPSE]和左心室分数 [LVEF])均离线评估。
该研究纳入了 117 名患者(年龄 57.2±19 岁;60.6%为男性)。t-IVT 与 SV、CO、MAP 和 CPI 呈负相关(r 值分别为-67%、-38%、-45%和-51%)。MAPSE 与 SV、CO、MAP 和 CPI 呈正相关(r 值分别为 43%、44%、34%和 31%)。LVEF 与任何参数均无相关性。多元分析证实,t-IVT 与 SV、CO、MAP 和 CPI 之间存在关联,且 t-IVT 与 MAP 的偏相关系数最高(R= -58%)。
MAPSE 和 t-IVT 是 2 种可重复且可靠的超声心动图指标,可反映心胸重症患者的收缩功能和心室效能,与血流动力学变量相关,而 LVEF 与任何参数均无相关性。