通气和近红外光谱反应同样可确定心力衰竭患者的无氧阈。

Ventilatory and Near-Infrared Spectroscopy Responses Similarly Determine Anaerobic Threshold in Patients With Heart Failure.

机构信息

Research Group on Cardiorespiratory Evaluation and Rehabilitation (GECARE), Physical Therapy Department and School of Physical Education and Sports, Federal University of Rio de Janeiro, Brazil (Drs Reis and Nasser); Pulmonary Function and Clinical Exercise Physiology Unit (SEFICE), Respiratory Division, Department of Medicine, Federal University of São Paulo (UNIFESP), Brazil (Drs Barroco, Berton, and Neder); Physical Therapy Department, College of Applied Health Sciences, University of Illinois, Chicago (Dr Arena); and Cardiopulmonary Physical Therapy Laboratory, Nucleus of Research in Physical Exercise, Physical Therapy Department, Federal University of São Carlos (UFSCar), Brazil (Dr Borghi-Silva).

出版信息

J Cardiopulm Rehabil Prev. 2020 Mar;40(2):E18-E21. doi: 10.1097/HCR.0000000000000462.

DOI:10.1097/HCR.0000000000000462

PMID:32118656

Abstract

PURPOSE

The present study compared the level of agreement of anaerobic threshold (AT) between ventilatory and near-infrared spectroscopy (NIRS) techniques in patients with chronic heart failure (CHF) and healthy subjects.

METHODS

Patients with CHF (n = 9) and a control group (CG; n = 14) underwent cardiopulmonary exercise testing on a cycle ergometer until physical exhaustion. Determination of AT was performed visually by (1) ventilatory-expired gas analysis curves and (2) oxyhemoglobin (O2Hb) and deoxyhemoglobin (HHb) curves assessed by NIRS.

RESULTS

The CHF group presented significantly lower oxygen consumption (O2), heart rate, and workload at AT when compared with the CG measured by NIRS (P < .05). However, the effect size, measured by the Cohen d, revealed large magnitude (>0.80) in both techniques when compared between CHF patients and the CG. In addition, ventilatory and NIRS techniques demonstrated significant and very strong/strong correlations for relative O2 (r = 0.91) and heart rate (r = 0.85) in the detection of AT in the CHF group.

CONCLUSION

Both ventilatory and NIRS assessments are correlated and there are no differences in the responses between CHF patients and healthy subjects in the determination of AT. These findings indicate both approaches may have utility in the assessment of submaximal exercise performance in patients with CHF.

摘要

目的

本研究比较了慢性心力衰竭（CHF）患者和健康受试者在无氧阈（AT）方面，通气和近红外光谱（NIRS）技术的一致性水平。

方法

CHF 患者（n=9）和对照组（CG；n=14）在功率自行车上进行心肺运动测试，直至体力衰竭。通过（1）通气呼出气体分析曲线和（2）NIRS 评估的氧合血红蛋白（O2Hb）和脱氧血红蛋白（HHb）曲线，对 AT 进行视觉确定。

结果

与 CG 相比，NIRS 测量的 CHF 组在 AT 时的耗氧量（O2）、心率和工作负荷显著降低（P<0.05）。然而，通过 Cohen d 测量的效应量表明，在 CHF 患者和 CG 之间比较时，两种技术都具有较大的幅度（>0.80）。此外，在 CHF 组中，通气和 NIRS 技术在检测 AT 时，相对 O2（r=0.91）和心率（r=0.85）的相关性显著且非常强/强。