患有和未患有自主神经病变的糖尿病患者对柠檬酸的咳嗽阈值
Cough threshold to citric acid in diabetic patients with and without autonomic neuropathy.
作者信息
Vianna L G, Gilbey S G, Barnes N C, Guy R J, Gray B J
机构信息
Department of Thoracic Medicine, King's College School of Medicine and Dentistry, London.
出版信息
Thorax. 1988 Jul;43(7):569-71. doi: 10.1136/thx.43.7.569.
The cough reflex has been investigated in insulin dependent diabetic patients with and without autonomic neuropathy. The cough response to inhaled citric acid was determined in eight patients with diabetes who had severe autonomic neuropathy and compared with that in 10 who had no evidence of neuropathy. The patients with autonomic neuropathy had a higher median threshold for the cough response to citric acid (median 50%, range 20- greater than 100%) than non-neuropathic control patients (median 10%, range 2-20%). These results suggest that vagal innervation of the bronchial tree is damaged by diabetic autonomic neuropathy.
对患有和未患有自主神经病变的胰岛素依赖型糖尿病患者的咳嗽反射进行了研究。测定了8例患有严重自主神经病变的糖尿病患者对吸入柠檬酸的咳嗽反应，并与10例无神经病变证据的患者进行了比较。自主神经病变患者对柠檬酸咳嗽反应的中位数阈值（中位数50%，范围20%-大于100%）高于无神经病变的对照患者（中位数10%，范围2%-20%）。这些结果表明，糖尿病自主神经病变会损害支气管树的迷走神经支配。
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