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[全膝关节置换翻修术后的并发症]

[Complications after Revision Total Knee Arthroplasties].

作者信息

Louda J, Kubát P, Pilný J

机构信息

Ortopedicko-traumatologické oddělení Nemocnice Havlíčkův Brod.

出版信息

Acta Chir Orthop Traumatol Cech. 2020;87(1):28-31.

Abstract

PURPOSE OF THE STUDY The failure of arthroplasties and above all the issue of infection and its detection have become an ever more frequently discussed problem. The purpose of our study was to determine the frequency and the type of complications after revision total knee arthroplasties and to compare them with the frequency of complications after primary implantations. MATERIAL AND METHODS In our group of patients followed up in the period from January 2007 to December 2016, in 50 patients the revision surgery was performed for aseptic loosening and in 24 patients for deep infection. In the case of revision surgery for aseptic loosening, in 18 patients original sterilised components were used as a spacer, in 6 patients an articulating cement spacer was applied. Only the complications resulting in the performance of further revision were included in the statistics. A total of 13 patients underwent a primary implantation at another centre. The number of revisions and the reason for implant failure were monitored. The results were compared with the frequency of revision surgeries after primary total knee arthroplasty, of which 2,436 were carried out in the referred to period. RESULTS Of 2,436 primary endoprostheses, altogether 3.1 % failed. In 50 (2.1 %) patients aseptic loosening was reported, 24 patients (1 %) suffered from infection. The median time from primary implantation to revision was 11 years for aseptic loosening, 2 years for infection. The most frequent cause of failure was aseptic loosening. In the group of patients who underwent a revision surgery for aseptic loosening, another revision was necessary in 6 cases (12 %), in the group of patients after the two-stage revision surgery for infection, in 9 cases (37.5 %). The most frequent reason for revision surgery was infection - in both the groups this was the reason for 67 % of revision surgeries. DISCUSSION Our results obtained with respect to primary as well as revision surgeries for aseptic loosening correspond with the results reported by other authors. In the case of two-stage revision implantation, the reported frequency of recurrent infections is the same, the frequency of revision surgeries for aseptic causes is slightly lower in our group. The most frequent causes of revision surgery are also in agreement. In the case of primary implantation, the patients most frequently suffer from aseptic loosening, after revision surgeries another revision surgery is most often performed due to infection. The literature refers to studies suggesting the potential use of original components as a spacer with the same success rate as that achieved with the cement spacer. The original components produced good results in two thirds of two-stage revision implantations, which is why we can agree with these studies. CONCLUSIONS The results clearly show a noticeable increase in the frequency of complications in revision surgeries compared to primary surgeries. In comparison with primary implantations, a subsequent revision after the revision implantation for aseptic loosening was necessary three times more frequently, after the two-stage revision implantation for infection it was ten times more frequently. As the most problematic complication can be considered the infection in case of primary as well as revision interventions. It is obvious that aseptic loosening of the primary implant usually occurs later (the median of 11 years) than the development of deep infection (the median of 2 years). Key words: total knee arthroplasty, revision, failure, complications, aseptic loosening, infection, spacer.

摘要

研究目的 关节置换术的失败,尤其是感染问题及其检测,已成为一个越来越常被讨论的问题。我们研究的目的是确定全膝关节翻修术后并发症的发生率和类型,并将其与初次植入术后并发症的发生率进行比较。材料与方法 在我们随访的一组患者中,2007年1月至2016年12月期间,50例患者因无菌性松动接受翻修手术,24例患者因深部感染接受翻修手术。在因无菌性松动进行翻修手术的病例中,18例患者使用原灭菌组件作为间隔物,6例患者应用了活动型骨水泥间隔物。统计中仅包括导致再次翻修的并发症。共有13例患者在另一个中心接受初次植入。监测翻修次数和植入失败原因。将结果与初次全膝关节置换术后翻修手术的发生率进行比较,在此期间共进行了2436例初次全膝关节置换术。结果 在2436例初次植入的假体中,共有3.1%失败。报告50例(2.1%)患者发生无菌性松动,24例(1%)患者发生感染。初次植入至翻修的中位时间,无菌性松动为11年,感染为2年。最常见的失败原因是无菌性松动。在因无菌性松动接受翻修手术的患者组中,6例(12%)需要再次翻修;在因感染接受两阶段翻修手术的患者组中,9例(37.5%)需要再次翻修。翻修手术最常见的原因是感染——在两组中,这都是67%翻修手术的原因。讨论 我们在初次及无菌性松动翻修手术方面获得的结果与其他作者报告的结果相符。在两阶段翻修植入的情况下,报告的复发性感染发生率相同,我们组中无菌性原因翻修手术的发生率略低。翻修手术最常见的原因也一致。在初次植入时,患者最常发生无菌性松动;翻修手术后,再次翻修手术最常因感染进行。文献中提到的研究表明,原组件作为间隔物可能具有与骨水泥间隔物相同的成功率。原组件在三分之二的两阶段翻修植入中取得了良好效果,这就是我们认同这些研究的原因。结论 结果清楚地表明,与初次手术相比,翻修手术并发症的发生率显著增加。与初次植入相比,因无菌性松动进行翻修植入后再次翻修的频率高出三倍,因感染进行两阶段翻修植入后再次翻修的频率高出十倍。在初次及翻修干预中,最成问题的并发症可认为是感染。显然,初次植入的无菌性松动通常比深部感染的发生时间晚(中位时间为11年)(深部感染中位时间为2年)。关键词:全膝关节置换术,翻修术,失败,并发症,无菌性松动,感染,间隔物

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