超声评估甲状腺乳头状癌患者的同步甲状腺结节：超声与病理的结节对结节分析。

Ultrasound Assessment of Synchronous Thyroid Nodules in Patients With Papillary Thyroid Cancer: A Nodule-by-nodule Analysis Between Ultrasound and Pathology.

机构信息

Department of Radiology, School of Medicine, Kyungpook National University Chilgok Hospital, Kyungpook National University, Daegu, Republic of Korea.

Department of Radiology, School of Medicine, Kyungpook National University Hospital, Kyungpook National University, Daegu, Republic of Korea

出版信息

Anticancer Res. 2020 Mar;40(3):1779-1786. doi: 10.21873/anticanres.14132.

DOI:10.21873/anticanres.14132

PMID:32132087

Abstract

BACKGROUND/AIM: The purpose of this study was to evaluate the diagnostic value of preoperative ultrasound (US) in the assessment of synchronous thyroid nodules in patients with papillary thyroid cancer (PTC) for determination of surgical extent.

PATIENTS AND METHODS

A total of 210 consecutive patients who were surgically diagnosed with PTC were included in this study. Synchronous nodules, divided into probably benign and suspicious nodules based on US findings, were correlated with pathologic results using a nodule-by-nodule analysis.

RESULTS

Among the 302 synchronous nodules in 129 patients, 83 (27.5%) synchronous nodules in 73 patients were diagnosed as malignant after surgery. Ipsilateral probably benign nodules on US were more likely to be malignant than contralateral probably benign nodules (ipsilateral, 10.6%; contralateral, 2.0%, p=0.015). The presence of suspicious contralateral nodules on US and the number of synchronous nodules were significant factors related to contralateral cancer (p<0.001 and 0.030).

CONCLUSION

For evaluation of synchronous nodules in PTC patients, US assessment for synchronous nodules can be applied for preserving the contralateral lobe.

摘要

背景/目的：本研究旨在评估术前超声（US）在评估甲状腺乳头状癌（PTC）患者同步甲状腺结节以确定手术范围方面的诊断价值。

患者与方法

本研究共纳入 210 例经手术诊断为 PTC 的连续患者。根据 US 结果将同步结节分为可能良性和可疑结节，并进行逐结节相关性分析，与病理结果进行比较。

结果

在 129 例患者的 302 个同步结节中，术后有 83 个（27.5%）同步结节被诊断为恶性。US 上同侧可能良性结节比对侧可能良性结节更有可能是恶性的（同侧，10.6%；对侧，2.0%，p=0.015）。US 上可疑对侧结节的存在和同步结节的数量是与对侧癌相关的显著因素（p<0.001 和 0.030）。