Connolly B, Fitzgerald R J, Guiney E J
Children's Research Centre, Our Lady's Hospital for Sick Children, Crumlin, Dublin, Ireland.
Z Kinderchir. 1988 Dec;43 Suppl 2:17-8. doi: 10.1055/s-2008-1044147.
This retrospective study aims to assess the efficacy of vesicostomy in the management of deteriorating upper renal tracts in patients with neuropathic bladders for whom intermittent self catheterization is not a clinical option. Between 1980-1987 vesicostomy was performed in 16 such patients (11 female, 5 male). Eleven had myelomeningocoele, 4 sacral anomalies and one cerebral palsy with scoliosis. All patients had urinary tract infections and deteriorating hydronephrosis and hydroureter (IVP, U/S); associated reflux in 13, impaired GFR in 4 and abnormal biochemistry in 8. The mean age at surgery was 3.3 years (8 mths. to 9 years). In all cases deterioration was arrested by vesicostomy. Fifteen patients showed structural or functional improvement and one stabilized. Late closure of the vesicostomy in two cases resulted in disimprovement of biochemical and radiological parameters. Acceptance of the vesicostomies was good. We advocate vesicostomy as an effective drainage procedure to preserve function in patients with neuropathic bladders and deteriorating renal tracts, in whom intermittent self catheterization is not a realistic alternative.
这项回顾性研究旨在评估膀胱造瘘术对神经源性膀胱患者上尿路恶化的治疗效果,对于这些患者而言,间歇性自我导尿并非临床可行的选择。1980年至1987年间,对16例此类患者(11例女性,5例男性)实施了膀胱造瘘术。其中11例患有脊髓脊膜膨出,4例有骶骨异常,1例患有脑瘫并伴有脊柱侧弯。所有患者均患有尿路感染且肾盂积水和输尿管积水不断恶化(静脉肾盂造影、超声检查);13例伴有反流,4例肾小球滤过率受损,8例生化指标异常。手术时的平均年龄为3.3岁(8个月至9岁)。在所有病例中,膀胱造瘘术均阻止了病情恶化。15例患者的结构或功能得到改善,1例病情稳定。2例患者膀胱造瘘术的后期闭合导致生化和放射学参数恶化。患者对膀胱造瘘术的接受度良好。我们主张将膀胱造瘘术作为一种有效的引流方法,用于保护神经源性膀胱且上尿路恶化、无法进行间歇性自我导尿的患者的肾功能。