Neurophysiology Department, Hospital Ángeles del Pedregal, México City, Mexico.
Neurology Department, National Institute of Neurology, Mexico City, Mexico.
J Clin Neurophysiol. 2021 May 1;38(3):231-236. doi: 10.1097/WNP.0000000000000689.
Intraoperative neurophysiological monitoring (IONM) is widely used to prevent nervous system injury during surgeries in elderly patients. However, there are no studies that describe the characteristics and changes in neurophysiological tests during the IONM of patients aged 60 years and older. The study aims to describe and compare IONM changes during surgeries in adult patients aged 18 to 59 years with those aged 60 years and older.
We performed a comparative retrospective study of patients aged 18 to 59 years versus those 60 aged years and older who underwent IONM during 2013 to 2018 in Mexico City. Sociodemographic characteristics were recorded and compared. Intraoperative neurophysiological monitoring techniques, their changes, and surgical procedures for both groups were analyzed and compared using descriptive statistics, Mann-Whitney U, Fisher, and χ2 tests. The sensitivity, specificity, and positive and negative predictive values were calculated.
In total, 195 patients were analyzed: 104 patients, 68.63 ± 6.54 years old (elderly group) and 91 patients, 42.3 ± 10.5 years old (younger group). No differences were found in the rates of signal change during IONM between the group of elderly patients and the younger group. The sensitivity, specificity, and positive and negative predictive values were 80%, 99%, 80%, and 99%, respectively.
Elderly patients have a similar rate of changes in IONM signals compared with younger patients during heterogeneous surgeries guided by IONM.
术中神经生理监测(IONM)广泛用于预防老年患者手术中的神经系统损伤。然而,目前还没有研究描述 60 岁及以上患者 IONM 期间神经生理测试的特征和变化。本研究旨在描述和比较 18 至 59 岁成年患者与 60 岁及以上患者在 IONM 期间手术的变化。
我们对 2013 年至 2018 年期间在墨西哥城接受 IONM 的 18 至 59 岁和 60 岁及以上患者进行了一项比较性回顾性研究。记录并比较了社会人口统计学特征。采用描述性统计、Mann-Whitney U、Fisher 和 χ2 检验对两组患者的术中神经生理监测技术、变化以及手术过程进行分析和比较。计算了灵敏度、特异性、阳性和阴性预测值。
共分析了 195 名患者:104 名患者,68.63 ± 6.54 岁(老年组)和 91 名患者,42.3 ± 10.5 岁(年轻组)。老年患者和年轻组在 IONM 期间信号变化率方面没有差异。灵敏度、特异性、阳性和阴性预测值分别为 80%、99%、80%和 99%。
在 IONM 指导下进行的异质手术中,老年患者的 IONM 信号变化率与年轻患者相似。