BRD4 Is Necessary for Differentiation Downstream of Epidermal Lineage-Determining Transcription Factors.
作者信息
Jones Jackson, Chen Yifang, Tiwari Manisha, Li Jingting, Ling Ji, Sen George L
机构信息
Department of Dermatology, Department of Cellular and Molecular Medicine, UCSD Stem Cell Program, University of California, San Diego, La Jolla, California, USA.
Department of Dermatology, Department of Cellular and Molecular Medicine, UCSD Stem Cell Program, University of California, San Diego, La Jolla, California, USA.
出版信息
J Invest Dermatol. 2020 Oct;140(10):2077-2081.e5. doi: 10.1016/j.jid.2020.01.030. Epub 2020 Mar 3.
Abstract
摘要
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本文引用的文献
1
BRD4 and Cancer: going beyond transcriptional regulation.
Mol Cancer. 2018 Nov 22;17(1):164. doi: 10.1186/s12943-018-0915-9.
2
Stretching the limits: from homeostasis to stem cell plasticity in wound healing and cancer.
Nat Rev Genet. 2018 May;19(5):311-325. doi: 10.1038/nrg.2018.9. Epub 2018 Feb 26.
3
Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis.
Nat Commun. 2017 Dec 20;8(1):2217. doi: 10.1038/s41467-017-02403-5.
4
Lineage-specific dynamic and pre-established enhancer-promoter contacts cooperate in terminal differentiation.
Nat Genet. 2017 Oct;49(10):1522-1528. doi: 10.1038/ng.3935. Epub 2017 Aug 14.
5
BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia.
Mol Cell. 2015 Jun 18;58(6):1028-39. doi: 10.1016/j.molcel.2015.04.011. Epub 2015 May 14.
6
A LncRNA-MAF:MAFB transcription factor network regulates epidermal differentiation.
Dev Cell. 2015 Mar 23;32(6):693-706. doi: 10.1016/j.devcel.2015.01.028.
7
ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes.
Genes Dev. 2014 Sep 15;28(18):2013-26. doi: 10.1101/gad.246579.114.
8
Genetic pathways in disorders of epidermal differentiation.
Trends Genet. 2013 Jan;29(1):31-40. doi: 10.1016/j.tig.2012.10.005. Epub 2012 Nov 8.
9
An integrated encyclopedia of DNA elements in the human genome.
Nature. 2012 Sep 6;489(7414):57-74. doi: 10.1038/nature11247.
10
GRHL3/GET1 and trithorax group members collaborate to activate the epidermal progenitor differentiation program.
PLoS Genet. 2012;8(7):e1002829. doi: 10.1371/journal.pgen.1002829. Epub 2012 Jul 19.
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