Balakrishnan Thalaivirithan Margabandu, Jayachandiran Anand Prasath, Hariraj Divya Devi, Jaganmohan Janadhanam
Department of Plastic and Faciomaxillary Surgery, Madras Medical College, Chennai, India.
J Craniofac Surg. 2020 Jun;31(4):e337-e343. doi: 10.1097/SCS.0000000000006276.
Microvascular free tissue transfer has revolutionized the management of complex composite head and neck defects.
To evaluate the functional and aesthetic outcomes in the primary reconstruction of post-excisional near total hemifacial defects with the chimeric anterolateral thigh flaps (cALT).
The author as a prelude to this clinical study has done a cadaveric study on the quadriceps artery angiosome. In this retrospective cohort study, data are collected from the records of 6 patients who had undergone primary cALT flap reconstruction for their post excisional near total hemifacial defects from January 2013 to December 2017. All 6 patients with various advanced malignancies involving the hemiface underwent wide local excision. Wide local excision resulted in the loss of skin and critical facial muscles that led to near total hemiface composite defects. Reconstructions were done with the cALT flaps that included segment of the vastus lateralis muscle harvested on its independent neurovascular perforator pedicle and the skin paddle on a separate perforator. In all cases, the facial nerve stumps were anastomosed to the nerve to vastus lateralis for reanimation of the face. In addition, 4 patients underwent primary radical neck dissection, but all had postoperative radiotherapy and chemotherapy.
All patients attained well-pronounced nasolabial fold, symmetrical smile, and good oral competence in an average period of 10.75 months post operatively. In an average of 22 months follow up, none of them had locoregional recurrences. None required any secondary procedures.
In the post excisional near total hemifacial composite defects, primary functional reconstruction with tailored cALT flaps can bring good aesthetic and functional results.
微血管游离组织移植彻底改变了复杂复合性头颈部缺损的治疗方式。
评估采用嵌合型股前外侧皮瓣(cALT)一期修复切除术后近全半侧面部缺损的功能和美学效果。
作为这项临床研究的前奏,作者对股四头肌动脉血管体进行了尸体研究。在这项回顾性队列研究中,收集了2013年1月至2017年12月期间6例因切除术后近全半侧面部缺损接受一期cALT皮瓣重建的患者的记录数据。所有6例患有累及半侧面部各种晚期恶性肿瘤的患者均接受了广泛局部切除。广泛局部切除导致皮肤和关键面部肌肉缺失,进而造成近全半侧面部复合缺损。采用cALT皮瓣进行重建,皮瓣包括在其独立神经血管穿支蒂上切取的股外侧肌段和在另一个穿支上的皮瓣。在所有病例中,将面神经残端与股外侧肌神经进行吻合以实现面部再支配。此外,4例患者接受了一期根治性颈清扫术,但均接受了术后放疗和化疗。
所有患者在术后平均10.75个月时均获得了明显的鼻唇沟、对称的笑容和良好的口腔功能。平均随访22个月,无一例出现局部复发。均无需进行任何二次手术。
在切除术后近全半侧面部复合缺损中,采用定制的cALT皮瓣进行一期功能重建可带来良好的美学和功能效果。