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[I级肥胖对视频腹腔镜手术期间呼吸力学的影响:前瞻性纵向研究]

[Impact of Grade I obesity on respiratory mechanics during video laparoscopic surgery: prospective longitudinal study].

作者信息

Araujo Orlandira Costa, Espada Eloisa Bonetti, Costa Fernanda Magalhães Arantes, Vigiato Julia Araujo, Carmona Maria José Carvalho, Otoch José Pinhata, Silva João Manoel, Martins Milton de Arruda

机构信息

Universidade de São Paulo (USP), Hospital Universitário (HU), São Paulo, SP, Brasil; Instituto de Assistência Médica do Servidor Público Estadual do Estado de São Paulo (IAMSPE), São Paulo, SP, Brasil.

Universidade de São Paulo (USP), Hospital Universitário (HU), São Paulo, SP, Brasil; Universidade de São Paulo (USP), Faculdade de Medicina (FM), Hospital das Clínicas (HC), São Paulo, SP, Brasil.

出版信息

Braz J Anesthesiol. 2020 Mar-Apr;70(2):90-96. doi: 10.1016/j.bjan.2019.12.001. Epub 2020 Feb 20.

Abstract

INTRODUCTION AND OBJECTIVES

The association pneumoperitoneum and obesity in video laparoscopy can contribute to pulmonary complications, but has not been well defined in specific groups of obese individuals. We assessed the effects of pneumoperitoneum in respiratory mechanics in Grade I obese compared to non-obese.

METHODS

Prospective study including 20 patients submitted to video laparoscopic cholecystectomy, normal spirometry, divided into non-obese (BMI ≤ 25 kg.m) and obese (BMI > 30 kg.mg), excluding Grade II and III obese. We measured pulmonary ventilation mechanics data before pneumoperitoneum (baseline), and five, fifteen and thirty minutes after peritoneal insufflation, and fifteen minutes after disinflation (final). Mean BMI of non-obese was 22.72 ± 1.43 kg.m and of the obese 31.78 ± 1.09 kg.m,  <  0.01. Duration of anesthesia and of peritoneal insufflation was similar between groups. Baseline pulmonary compliance (Crs) of the obese (38.3 ± 8.3 mL.cm HO) was lower than of the non-obese (47.4 ± 5.7 mL.cm HO),  =  0.01. After insufflation, Crs decreased in both groups and remained even lower in the obese at all moments assessed (GLM  <  0.01). Respiratory system peak pressure and plateau pressure were higher in the obese, albeit variations were similar at moments analyzed (GLM  >  0.05). The same occurred with elastic pressure, higher in the obese at all times (GLM  =  0.04), and resistive pressure showed differences in variations between groups during pneumoperitoneum (GLM  =  0,05).

CONCLUSIONS

Grade I obese presented more changes in pulmonary mechanics than the non-obese during video laparoscopies and the fact requires mechanical ventilation-related care.

摘要

引言与目的

视频腹腔镜手术中的气腹与肥胖之间的关联可能导致肺部并发症,但在特定肥胖个体群体中尚未得到明确界定。我们评估了与非肥胖者相比,I级肥胖者气腹对呼吸力学的影响。

方法

前瞻性研究,纳入20例行视频腹腔镜胆囊切除术、肺功能正常的患者,分为非肥胖组(BMI≤25kg/m²)和肥胖组(BMI>30kg/m²),排除II级和III级肥胖者。我们在气腹前(基线)、腹腔充气后5分钟、15分钟和30分钟以及放气后15分钟(最终)测量肺通气力学数据。非肥胖组的平均BMI为22.72±1.43kg/m²,肥胖组为31.78±1.09kg/m²,P<0.01。两组间麻醉时间和腹腔充气时间相似。肥胖组的基线肺顺应性(Crs)(38.3±8.3mL/cmH₂O)低于非肥胖组(47.4±5.7mL/cmH₂O),P=0.01。充气后,两组的Crs均下降,且在所有评估时间点肥胖组的Crs仍更低(广义线性模型,P<0.01)。肥胖组的呼吸系统峰值压力和平台压力更高,尽管在分析的各时间点变化相似(广义线性模型,P>0.05)。弹性压力情况相同,肥胖组在所有时间均更高(广义线性模型,P=0.04),阻力压力在气腹期间两组间变化存在差异(广义线性模型,P=0.05)。

结论

在视频腹腔镜手术期间,I级肥胖者的肺力学变化比非肥胖者更多,这一情况需要与机械通气相关的护理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54ba/9373104/bc5dec7d98de/gr2.jpg

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