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加味三黄泻心汤加其他药草联合使用的效果。 你提供的原文似乎不完整,若你能补充完整内容,我可提供更准确的翻译。

Effect of modified Sanhuang Xiexin Tang plus additional herbs combined with.

作者信息

Yao Xinjie, Li Yan

机构信息

Department of Gastroenterology, Shengjing Hospital Affiliated to China Medical University, Shenyang 110002, China.

出版信息

J Tradit Chin Med. 2018 Feb;38(1):101-106.

Abstract

OBJECTIVE

To determine the effectiveness of modified Sanhuang Xiexin Tang (SHXXT) plus additional herbs (MSAH) combined with ""standard triple therapy"" for eradication of Helicobacter pylori (H.pylori) and amelioration of related symptoms in comparison with standard triple and standard quadruple therapies.

METHODS

From October 2015 to May 2016, we recruited patients with dyspepsia symptoms confirmed to have H.pylori infection by the 13C urea breath test in our outpatient clinic. Patients were randomly divided into three treatment groups: Nexium? standard triple therapy (group A; EAC); Nexium® standard quadruple therapy (group B; EBAC); or Nexium? standard triple therapy combined with MSAH (group C; EAC+MSAH). Comparisons of Hpylori eradication and symptom amelioration rates were made among the three groups at 2 or 6 weeks after group assignment.

RESULTS

There was no difference in H. pylori eradication rates between groups B (EBAC) and C (EAC+MSAH) (P = 0.486), and eradication rates in groups B and C were significantly higher than that in group A (EAC) (P A vs B = 0.001; P A vs C = 0.003). There was no difference in the total symptom score among the groups before treatment. In all groups, the total symptom scores after treatment (2 or 6 weeks after group assignment) were significantly lower than those before treatment (P<65308; 0.001 for all). However, group C (EAC + MSAH) demonstrated superior total symptom scores and symptom amelioration rates than groups A (EAC) and B (EBAC). Group B also demonstrated better scores and rates than group A. There was no difference in symptom amelioration rates at 2 and 6 weeks within each group.

CONCLUSION

There is no difference between MSAH combined with standard triple therapy and standard quadruple therapy containing bismuth with regard to H.pylori eradication rate. However, MSAH combined with standard triple therapy has a higher symptom amelioration rate and therefore appears to be an ideal treatment scheme for H.pylori eradication.

摘要

目的

比较改良三黄泻心汤加味(MSAH)联合“标准三联疗法”与标准三联疗法及标准四联疗法根除幽门螺杆菌(H.pylori)及改善相关症状的疗效。

方法

2015年10月至2016年5月,在我院门诊招募经13C尿素呼气试验确诊为H.pylori感染的消化不良症状患者。将患者随机分为三组:耐信标准三联疗法(A组;EAC);耐信标准四联疗法(B组;EBAC);或耐信标准三联疗法联合MSAH(C组;EAC+MSAH)。在分组后2周或6周对三组的Hpylori根除率和症状改善率进行比较。

结果

B组(EBAC)和C组(EAC+MSAH)的幽门螺杆菌根除率无差异(P = 0.486),B组和C组的根除率显著高于A组(EAC)(P A与B比较 = 0.001;P A与C比较 = 0.003)。治疗前各组总症状评分无差异。所有组治疗后(分组后2周或6周)的总症状评分均显著低于治疗前(P<65308;均P<0.001)。然而,C组(EAC + MSAH)的总症状评分和症状改善率优于A组(EAC)和B组(EBAC)。B组的评分和改善率也优于A组。各组在2周和6周时的症状改善率无差异。

结论

MSAH联合标准三联疗法与含铋的标准四联疗法在幽门螺杆菌根除率方面无差异。然而,MSAH联合标准三联疗法具有更高的症状改善率,因此似乎是根除幽门螺杆菌的理想治疗方案。

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