犬的睑板腺缺失相关的组织病理学变化。
Histopathologic changes associated with Meibomian Gland dropout in a dog.
机构信息
Yakumo Animal Hospital, Hokkaido, Japan.
Itoh Clinic, Saitama, Japan.
出版信息
Vet Ophthalmol. 2020 May;23(3):575-578. doi: 10.1111/vop.12754. Epub 2020 Mar 18.
PURPOSE
To perform histopathologic analysis of tissue manifesting meibomian gland dropout on noncontact infrared meibography in a dog.
METHODS
A 14-year-old intact male Cairn terrier was evaluated at Triangle Animal Eye Clinic for dense corneal opacity of the right eye. A complete ocular examination was performed, including slit-lamp biomicroscopy, tonometry, and noncontact meibography. Pigmentary glaucoma with elevation of intraocular pressure was diagnosed, and meibography revealed morphological changes suggestive of gland dropout in the middle of the upper right eyelid.
RESULTS
The globe was enucleated by the transpalpebral method, and palpebral tissue was subjected to histopathologic analysis. The analysis revealed an almost complete loss of meibomian gland structure accompanied by slight enlargement and proliferation of fibroblasts as well as by infiltration of plasma cells and lymphocytes.
CONCLUSIONS
Meibomian gland dropout as detected by meibography can be associated with chronic inflammation.
目的
对非接触式红外睑板腺照相术显示的睑板腺缺失的组织进行组织病理学分析。
方法
一只 14 岁的未绝育雄性凯恩梗在 Triangle 动物眼科诊所因右眼角膜混浊就诊。进行了全面的眼部检查，包括裂隙灯生物显微镜检查、眼压测量和非接触式睑板腺照相术。诊断为色素性青光眼伴眼压升高，睑板腺照相术显示右上眼睑中部有形态学改变，提示腺体缺失。
结果
经经皮眼球摘除法摘除眼球，并对眼睑组织进行组织病理学分析。分析显示，睑板腺结构几乎完全缺失，伴有成纤维细胞轻度肿大和增生，以及浆细胞和淋巴细胞浸润。
结论
睑板腺照相术检测到的睑板腺缺失可能与慢性炎症有关。
Zotero 插件