Yamagata Kazuaki, Hirose Yohsuke, Tanaka Kenji, Yoshida Miki, Ohnuki Tomotaka, Sendo Ryozo, Niwa Hitoshi, Sugimura Mitsutaka
Sakai Special Needs Dental Clinic, Sakai, Japan.
Department of Dental Anesthesiology, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Anesth Prog. 2020 Spring;67(1):16-22. doi: 10.2344/anpr-66-03-02.
Vagal nerve stimulation (VNS) is an established adjunctive treatment for patients with refractory epilepsy. VNS is effective in many cases, but few patients achieve complete elimination of seizures. Furthermore, VNS can cause respiratory complications, such as obstructive sleep apnea. This report describes the successful anesthetic management of a 28-year-old woman with a VNS device who underwent dental treatment under general anesthesia. She was morbidly obese and had undergone placement of a VNS device secondary to drug-resistant epilepsy 2 years prior but continued to experience daily epileptic seizures. Because of concerns about the risk of perioperative epileptic seizures and apneic events, use of the dedicated VNS device magnet was planned if such complications occurred. Total intravenous anesthesia was induced with propofol and remifentanil and a bispectral index sensor was used to help monitor brain wave activity for evidence of seizures along with the depth of anesthesia. Postoperatively, the patient received positional therapy and supplemental oxygen while being closely monitored in recovery. The anesthetic course was completed uneventfully without need of the VNS magnet. A thorough understanding of the mechanics of a VNS device, including proper use of the VNS magnet, is critical for an anesthesiologist during the perioperative period.
迷走神经刺激术(VNS)是难治性癫痫患者已确立的辅助治疗方法。VNS在许多情况下是有效的,但很少有患者能完全消除癫痫发作。此外,VNS可引起呼吸并发症,如阻塞性睡眠呼吸暂停。本报告描述了一名28岁植入VNS装置的女性患者在全身麻醉下接受牙科治疗时成功的麻醉管理。她病态肥胖,2年前因耐药性癫痫植入了VNS装置,但仍每天发作癫痫。由于担心围手术期癫痫发作和呼吸暂停事件的风险,计划在发生此类并发症时使用专用的VNS装置磁铁。采用丙泊酚和瑞芬太尼诱导全静脉麻醉,并使用脑电双频指数传感器来帮助监测脑电波活动,以发现癫痫发作迹象以及麻醉深度。术后,患者接受体位治疗并补充氧气,同时在恢复过程中进行密切监测。麻醉过程顺利完成,无需使用VNS磁铁。对于麻醉医生来说,在围手术期全面了解VNS装置的机制,包括正确使用VNS磁铁,至关重要。