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Impact of vagus nerve stimulation on sleep-related breathing disorders in adults with epilepsy.迷走神经刺激对癫痫成年患者睡眠相关呼吸障碍的影响。
Epilepsy Behav. 2018 Feb;79:126-129. doi: 10.1016/j.yebeh.2017.10.040. Epub 2017 Dec 26.
2
Outcome of vagus nerve stimulation for drug-resistant epilepsy: the first three years of a prospective Japanese registry.迷走神经刺激术治疗耐药性癫痫的疗效:日本前瞻性登记研究的头三年
Epileptic Disord. 2017 Sep 1;19(3):327-338. doi: 10.1684/epd.2017.0929.
3
Complications and safety of vagus nerve stimulation: 25 years of experience at a single center.迷走神经刺激术的并发症与安全性:单一中心25年的经验
J Neurosurg Pediatr. 2016 Jul;18(1):97-104. doi: 10.3171/2016.1.PEDS15534. Epub 2016 Mar 25.
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Electroencephalography of Seizure-Like Movements During General Anesthesia with Propofol: Seizures or Nonepileptic Events?丙泊酚全身麻醉期间类癫痫样运动的脑电图:癫痫发作还是非癫痫事件?
A A Case Rep. 2015 Dec 1;5(11):195-8. doi: 10.1213/XAA.0000000000000212.
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Modern inhalational anesthetics for refractory status epilepticus.用于难治性癫痫持续状态的现代吸入性麻醉剂。
Can J Neurol Sci. 2015 Mar;42(2):106-15. doi: 10.1017/cjn.2014.121. Epub 2015 Jan 9.
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Practice guidelines for the perioperative management of patients with obstructive sleep apnea: an updated report by the American Society of Anesthesiologists Task Force on Perioperative Management of patients with obstructive sleep apnea.阻塞性睡眠呼吸暂停患者围手术期管理实践指南:美国麻醉医师协会阻塞性睡眠呼吸暂停患者围手术期管理特别工作组的最新报告
Anesthesiology. 2014 Feb;120(2):268-86. doi: 10.1097/ALN.0000000000000053.
7
Bispectral index changes during generalised tonic-clonic seizures.
Anaesthesia. 2013 Oct;68(10):1084-5. doi: 10.1111/anae.12427.
8
Epileptogenic effect of sevoflurane: determination of the minimal alveolar concentration of sevoflurane associated with major epileptoid signs in children.七氟醚的致痫作用:确定与儿童主要癫痫样体征相关的七氟醚最小肺泡浓度。
Anesthesiology. 2012 Dec;117(6):1253-61. doi: 10.1097/ALN.0b013e318273e272.
9
Obstructive sleep apnea and respiratory complications associated with vagus nerve stimulators.与迷走神经刺激器相关的阻塞性睡眠呼吸暂停和呼吸并发症。
J Clin Sleep Med. 2011 Aug 15;7(4):401-7. doi: 10.5664/JCSM.1204.
10
Epilepsy and anesthesia.
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一名佩戴迷走神经刺激器患者的麻醉管理

Anesthetic Management of a Patient With a Vagal Nerve Stimulator.

作者信息

Yamagata Kazuaki, Hirose Yohsuke, Tanaka Kenji, Yoshida Miki, Ohnuki Tomotaka, Sendo Ryozo, Niwa Hitoshi, Sugimura Mitsutaka

机构信息

Sakai Special Needs Dental Clinic, Sakai, Japan.

Department of Dental Anesthesiology, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.

出版信息

Anesth Prog. 2020 Spring;67(1):16-22. doi: 10.2344/anpr-66-03-02.

DOI:10.2344/anpr-66-03-02
PMID:32191509
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7083113/
Abstract

Vagal nerve stimulation (VNS) is an established adjunctive treatment for patients with refractory epilepsy. VNS is effective in many cases, but few patients achieve complete elimination of seizures. Furthermore, VNS can cause respiratory complications, such as obstructive sleep apnea. This report describes the successful anesthetic management of a 28-year-old woman with a VNS device who underwent dental treatment under general anesthesia. She was morbidly obese and had undergone placement of a VNS device secondary to drug-resistant epilepsy 2 years prior but continued to experience daily epileptic seizures. Because of concerns about the risk of perioperative epileptic seizures and apneic events, use of the dedicated VNS device magnet was planned if such complications occurred. Total intravenous anesthesia was induced with propofol and remifentanil and a bispectral index sensor was used to help monitor brain wave activity for evidence of seizures along with the depth of anesthesia. Postoperatively, the patient received positional therapy and supplemental oxygen while being closely monitored in recovery. The anesthetic course was completed uneventfully without need of the VNS magnet. A thorough understanding of the mechanics of a VNS device, including proper use of the VNS magnet, is critical for an anesthesiologist during the perioperative period.

摘要

迷走神经刺激术(VNS)是难治性癫痫患者已确立的辅助治疗方法。VNS在许多情况下是有效的,但很少有患者能完全消除癫痫发作。此外,VNS可引起呼吸并发症,如阻塞性睡眠呼吸暂停。本报告描述了一名28岁植入VNS装置的女性患者在全身麻醉下接受牙科治疗时成功的麻醉管理。她病态肥胖,2年前因耐药性癫痫植入了VNS装置,但仍每天发作癫痫。由于担心围手术期癫痫发作和呼吸暂停事件的风险,计划在发生此类并发症时使用专用的VNS装置磁铁。采用丙泊酚和瑞芬太尼诱导全静脉麻醉,并使用脑电双频指数传感器来帮助监测脑电波活动,以发现癫痫发作迹象以及麻醉深度。术后,患者接受体位治疗并补充氧气,同时在恢复过程中进行密切监测。麻醉过程顺利完成,无需使用VNS磁铁。对于麻醉医生来说,在围手术期全面了解VNS装置的机制,包括正确使用VNS磁铁,至关重要。