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妊娠合并强直性肌营养不良症

Myotonic muscular dystrophy in pregnancy.

作者信息

Hilliard G D, Harris R E, Gilstrap L C, Shoumarker R D

出版信息

South Med J. 1977 Apr;70(4):446-7. doi: 10.1097/00007611-197704000-00025.

Abstract

Myotonic muscular dystrophy is an autosomal dominant disease inherited with variable penetrance. With pregnancy, the myotonia and muscle weakness may increase. There is also an increased incidence of abortion, prematurity, fetal death, labor dysfunction, and postpartum hemorrhage. A description of two pregnant patients and a review of the literature illustrate the interaction of the disease and pregnancy.

摘要

强直性肌营养不良症是一种常染色体显性疾病,其遗传具有可变的外显率。怀孕时,肌强直和肌无力可能会加重。流产、早产、胎儿死亡、分娩功能障碍及产后出血的发生率也会增加。对两名怀孕患者的描述及文献回顾说明了该疾病与妊娠之间的相互影响。

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