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Plasticity in Motion: Shape-Shifting Lgr5Cells Initiate Colorectal Cancer Metastasis.
Cell Stem Cell. 2020 Apr 2;26(4):469-471. doi: 10.1016/j.stem.2020.03.007.
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Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer.
Cell Stem Cell. 2020 Apr 2;26(4):569-578.e7. doi: 10.1016/j.stem.2020.02.008. Epub 2020 Mar 12.
3
[Expression of stem cell markers CD44 and Lgr5 in colorectal cancer and its relationship with lymph node and liver metastasis].
Zhonghua Yi Xue Za Zhi. 2018 Sep 25;98(36):2899-2904. doi: 10.3760/cma.j.issn.0376-2491.2018.36.005.
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GPR56 Drives Colorectal Tumor Growth and Promotes Drug Resistance through Upregulation of MDR1 Expression via a RhoA-Mediated Mechanism.
Mol Cancer Res. 2019 Nov;17(11):2196-2207. doi: 10.1158/1541-7786.MCR-19-0436. Epub 2019 Aug 23.
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Lgr5 is a potential marker of colorectal carcinoma stem cells that correlates with patient survival.
World J Surg Oncol. 2012 Nov 15;10:244. doi: 10.1186/1477-7819-10-244.
7
Intestinal stem cell marker LGR5 expression during gastric carcinogenesis.
World J Gastroenterol. 2013 Dec 14;19(46):8714-21. doi: 10.3748/wjg.v19.i46.8714.
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Upregulation of circulating cancer stem cell marker, DCLK1 but not Lgr5, in chemoradiotherapy-treated colorectal cancer patients.
Tumour Biol. 2015 Jun;36(6):4801-10. doi: 10.1007/s13277-015-3132-9. Epub 2015 Jan 29.
9
Lgr5+CD44+EpCAM+ Strictly Defines Cancer Stem Cells in Human Colorectal Cancer.
Cell Physiol Biochem. 2018;46(2):860-872. doi: 10.1159/000488743. Epub 2018 Mar 29.

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L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer.
Nat Cancer. 2020 Jan;1(1):28-45. doi: 10.1038/s43018-019-0006-x. Epub 2020 Jan 13.
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Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer.
Cell Stem Cell. 2020 Apr 2;26(4):569-578.e7. doi: 10.1016/j.stem.2020.02.008. Epub 2020 Mar 12.
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Ascl2-Dependent Cell Dedifferentiation Drives Regeneration of Ablated Intestinal Stem Cells.
Cell Stem Cell. 2020 Mar 5;26(3):377-390.e6. doi: 10.1016/j.stem.2019.12.011. Epub 2020 Feb 20.
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Cellular Plasticity in Intestinal Homeostasis and Disease.
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Specific Labeling of Stem Cell Activity in Human Colorectal Organoids Using an ASCL2-Responsive Minigene.
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EMT, CSCs, and drug resistance: the mechanistic link and clinical implications.
Nat Rev Clin Oncol. 2017 Oct;14(10):611-629. doi: 10.1038/nrclinonc.2017.44. Epub 2017 Apr 11.
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A distinct role for Lgr5 stem cells in primary and metastatic colon cancer.
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Crypt stem cells as the cells-of-origin of intestinal cancer.
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Identification of stem cells in small intestine and colon by marker gene Lgr5.
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Stem cells, cancer, and cancer stem cells.
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