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腹腔镜袖状胃切除术治疗超病态肥胖与病态肥胖患者的镇痛需求降低。

Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy.

机构信息

Department of Anaesthesia, Assiut University Hospitals, Assiut, Egypt.

Anaesthesia Dept., Al Wakrah Hospital, HAMAD Medical Corporation, P.O. Box 82228, Doha, Qatar.

出版信息

Obes Surg. 2020 Jul;30(7):2715-2722. doi: 10.1007/s11695-020-04559-4.

Abstract

BACKGROUND

Scarce data exists about analgesic requirements in super morbidly obese (SMO) patients who underwent sleeve gastrectomy. We attempted to investigate analgesic requirements for SMO, when compared with morbidly obese (MO) individuals who underwent sleeve gastrectomy and its impact on postoperative outcome.

METHODS

We studied 279 consecutive patients (183 MO, 96 SMO) who underwent bariatric surgery. Data analysis included perioperative anaesthetic management, analgesic consumptions, opioids side effects, and ICU admission.

RESULTS

The SMO group showed higher patients with asthma, epilepsy, obstructive sleep apnoea (OSA), and ASA III percentages (P = 0.014, P = 0.016, P ˂ 0.001, and P ˂ 0.001, respectively). There were no significant differences in the total morphine consumption intraoperatively, or after 24 h. However, reduced consumption of intraoperative fentanyl and morphine in SMO when calculated per total body weight (TBW) (P = 0.004 and P = 0.001, respectively). At PACU, tramadol consumption per TBW and lean body mass (LBM) were significantly reduced in SMO (P = 0.001 and P = 0.025, respectively). Paracetamol consumption was significantly reduced in the SMO group (P = 0.04). They showed higher comorbidities (P ˂ 0.001), longer anaesthesia time (P = 0.033), and greater ICU admissions (P ˂ 0.001). Vomiting was higher in the MO group (P = 0.004). Both groups showed comparable pain scores (P = 0.558) and PACU stay time (P = 0.060).

CONCLUSIONS

Super morbidly obese patients required fewer opioids and analgesics perioperatively. They exhibited higher comorbidities with greater anaesthesia time and ICU admissions. PACU stay time and pain scores were comparable.

摘要

背景

关于接受袖状胃切除术的超级肥胖(SMO)患者的镇痛需求,数据很少。我们试图研究 SMO 的镇痛需求,并与接受袖状胃切除术的病态肥胖(MO)个体进行比较,以及对术后结果的影响。

方法

我们研究了 279 例连续接受减重手术的患者(183 例 MO,96 例 SMO)。数据分析包括围手术期麻醉管理、镇痛消耗、阿片类药物副作用和 ICU 入院情况。

结果

SMO 组的哮喘、癫痫、阻塞性睡眠呼吸暂停(OSA)和 ASA III 比例较高(P=0.014、P=0.016、P<0.001 和 P<0.001)。术中或术后 24 小时总吗啡消耗量无显著差异。然而,当按总体重(TBW)计算时,SMO 术中芬太尼和吗啡的消耗减少(P=0.004 和 P=0.001)。在 PACU,SMO 中每 TBW 和瘦体重(LBM)消耗的曲马多明显减少(P=0.001 和 P=0.025)。SMO 组的对乙酰氨基酚消耗明显减少(P=0.04)。SMO 组的合并症较多(P<0.001),麻醉时间较长(P=0.033),ICU 入院率较高(P<0.001)。MO 组呕吐发生率较高(P=0.004)。两组的疼痛评分(P=0.558)和 PACU 停留时间(P=0.060)相当。

结论

超级肥胖患者围手术期需要较少的阿片类药物和镇痛药。他们的合并症较多,麻醉时间和 ICU 入院率较高。PACU 停留时间和疼痛评分相当。

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