多巴酚丁胺负荷试验对缺血患者涡流形成时间的影响。
The Effect of Dobutamine Stress Testing on Vortex Formation Time in Patients Evaluated for Ischemia.
机构信息
First Department of Cardiology, Hippokration General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Cardiovascular Imaging Section, 401 General Military Hospital of Athens, Athens, Greece.
出版信息
J Cardiovasc Transl Res. 2021 Aug;14(4):735-743. doi: 10.1007/s12265-020-09998-z. Epub 2020 Apr 6.
Vortex formation time (VFT) is a dimensionless index used to quantify duration of vortex ring formation during diastole. We sought to investigate the effect of pharmaceutical stress on VFT in patients evaluated for ischemia. For this purpose, a standard dobutamine stress echo (DSE) protocol was performed in 50 consecutive patients, and VFT was calculated at rest and at peak. VFT was calculated from echocardiography measurements using a previously developed mathematical equation. VFTi was calculated as the percentage of change of VFT, compared with VFT. Mean VFT was 2.46 (0.73) and mean VFT 1.67 (0.57) with mean VFT - 30.0% (19.8). In 14 (28%) patients, an ischemic response (DSE+) was documented. VFTi was significantly lower in DSE+ patients a finding which remained significant in the multivariate analysis after adjusting for age, sex, hypertension, diabetes, history of coronary artery disease, and relative increase of heart rate during stress. Graphical Abstract.
涡旋形成时间（VFT）是一个无量纲指数，用于量化舒张期涡旋环形成的持续时间。我们旨在研究药物应激对缺血患者 VFT 的影响。为此，对 50 例连续患者进行了标准多巴酚丁胺负荷超声心动图（DSE）检查，并在静息和峰值时计算 VFT。VFT 是使用先前开发的数学方程从超声心动图测量值计算得出的。VFTi 计算为 VFT 的百分比变化，与 VFT 相比。平均 VFT 为 2.46（0.73），平均 VFT 为 1.67（0.57），平均 VFT 为-30.0%（19.8）。在 14 名（28%）患者中，记录到缺血反应（DSE+）。在 DSE+患者中，VFTi 明显较低，这一发现在调整年龄、性别、高血压、糖尿病、冠心病病史和应激期间心率的相对增加后，在多变量分析中仍然显著。
Zotero 插件