立体定向消融放疗用于胃肠道间质瘤骨转移：病例报告及文献复习
Stereotactic ablative radiotherapy for bone metastasis of gastrointestinal stromal tumor: Case report and review of the literature.
作者信息
Yilmaz Melek Tugce, Gultekin Melis, Yalcin Suayib, Tuncel Murat, Gedikoglu Gokhan, Yildiz Ferah, Cengiz Mustafa
机构信息
Hacettepe University Faculty of Medicine, Department of Radiation Oncology, Ankara, Turkey.
Hacettepe University Faculty of Medicine, Department of Medical Oncology, Ankara, Turkey.
出版信息
Rep Pract Oncol Radiother. 2020 May-Jun;25(3):331-335. doi: 10.1016/j.rpor.2020.02.013. Epub 2020 Feb 24.
Abstract
BACKGROUND
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. These tumors are rare and only make bone metastases at a rate of 5%.
CASE SUMMARY
A 31-year-old male with a GIST presented with solitary bone metastasis at the right iliac bone. We performed stereotactic ablative radiotherapy (SABR) and achieved excellent local control. Herein, our case is presented, and a short review of the literature is carried out.
CONCLUSION
SABR should be considered as a treatment option in GIST with bone metastasis.
摘要
背景
胃肠道间质瘤（GISTs）是胃肠道最常见的间充质肿瘤。这些肿瘤较为罕见，发生骨转移的比例仅为5%。
病例摘要
一名31岁患有胃肠道间质瘤的男性出现右髂骨孤立性骨转移。我们进行了立体定向消融放疗（SABR）并实现了良好的局部控制。在此，我们展示该病例并对文献进行简要回顾。
结论
对于发生骨转移的胃肠道间质瘤，应考虑将立体定向消融放疗作为一种治疗选择。
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本文引用的文献
1
Stereotactic ablative radiotherapy versus standard of care palliative treatment in patients with oligometastatic cancers (SABR-COMET): a randomised, phase 2, open-label trial.
Lancet. 2019 May 18;393(10185):2051-2058. doi: 10.1016/S0140-6736(18)32487-5. Epub 2019 Apr 11.
2
Metastatic pattern and prognosis of gastrointestinal stromal tumor (GIST): a SEER-based analysis.
Clin Transl Oncol. 2019 Dec;21(12):1654-1662. doi: 10.1007/s12094-019-02094-y. Epub 2019 Mar 23.
3
Clinical and pathological characteristics of gastrointestinal stromal tumor (GIST) metastatic to bone.
Virchows Arch. 2017 Jul;471(1):77-90. doi: 10.1007/s00428-017-2138-7. Epub 2017 May 9.
4
Radiotherapy in the management of gist: state of the art and new potential scenarios.
Clin Sarcoma Res. 2017 Jan 10;7:1. doi: 10.1186/s13569-016-0065-z. eCollection 2017.
5
Skull Metastasis of Gastric Gastrointestinal Stromal Tumor Successfully Managed by Surgery.
J Korean Neurosurg Soc. 2017 Jan 1;60(1):94-97. doi: 10.3340/jkns.2014.0506.007. Epub 2016 Dec 29.
6
Metastatic Gastrointestinal Stromal Tumor to the Skull.
World Neurosurg. 2016 May;89:725.e11-6. doi: 10.1016/j.wneu.2016.01.019. Epub 2016 Jan 22.
7
Two cases of gastrointestinal stromal tumor of the small intestine with liver and bone metastasis.
Ann Transl Med. 2015 Oct;3(17):259. doi: 10.3978/j.issn.2305-5839.2015.09.46.
8
The standard diagnosis, treatment, and follow-up of gastrointestinal stromal tumors based on guidelines.
Gastric Cancer. 2016 Jan;19(1):3-14. doi: 10.1007/s10120-015-0526-8. Epub 2015 Aug 15.
9
Radiotherapy for GIST progressing during or after tyrosine kinase inhibitor therapy: A prospective study.
Radiother Oncol. 2015 Aug;116(2):233-8. doi: 10.1016/j.radonc.2015.07.025. Epub 2015 Jul 27.
10
Bone metastasis of a gastrointestinal stromal tumor: A report of two cases.
Oncol Lett. 2015 Apr;9(4):1814-1818. doi: 10.3892/ol.2015.2976. Epub 2015 Feb 17.
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