Ravindran Deepak M, Ravi Shravanthy, Santhanakrishnan Muthukumar, Sk Balaji
Periodontology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Cureus. 2020 Feb 27;12(2):e7118. doi: 10.7759/cureus.7118.
Neurofibromatosis (NF) is a genetic disorder that presents as benign tumours of the nervous system originating from the nerve sheath. It is of three types: Type I, Type II and Schwannomatosis. Type I Neurofibromatosis or von Recklinghausen's disease is the most common type of neurofibromatosis seen and it accounts for 90% of all cases seen. It can be seen as light brown pigmentation spots (Café-au-lait) on the skin and multiple small tumours among the nerves. Oral manifestations of NF are very rare and can be seen as sessile lesion in the tongue or the gingiva. The major complaints of the oral manifestations include difficulty in speech and mastication which it results in progression of periodontal disease. Here, we present a case report of Type I NF which presented as a sessile lesion in the right maxillary gingiva, for which we performed an excisional biopsy using LASER.
神经纤维瘤病(NF)是一种遗传性疾病,表现为起源于神经鞘的神经系统良性肿瘤。它有三种类型:I型、II型和施万细胞瘤病。I型神经纤维瘤病或冯·雷克林豪森病是最常见的神经纤维瘤病类型,占所有病例的90%。它可表现为皮肤上的浅棕色色素沉着斑(牛奶咖啡斑)和神经间的多个小肿瘤。NF的口腔表现非常罕见,可表现为舌部或牙龈的 sessile 病变。口腔表现的主要主诉包括言语和咀嚼困难,这会导致牙周病进展。在此,我们报告一例I型NF病例,表现为右上颌牙龈的 sessile 病变,我们使用激光对其进行了切除活检。