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药物性线状IgA大疱性皮肤病1例。

A Case of Drug-induced Linear IgA Bullous Dermatosis.

作者信息

Dessie Sofanit A, Singh Davinder, Dobariya Varun, Evans Derek, He Peimei

机构信息

Internal Medicine, Marshall University, Joan C. Edwards School of Medicine, Huntington, USA.

Medicine, Cabell Huntington Hospital, Huntington, USA.

出版信息

Cureus. 2020 Mar 4;12(3):e7175. doi: 10.7759/cureus.7175.

Abstract

Linear immunoglobulin A (IgA) bullous dermatosis (LABD) presents as a rare autoimmune disease that can either occur spontaneously or induced by certain drugs, the most common of which is vancomycin. LABD is a subepidermal blistering disease that is diagnosed by detecting linear IgA bands along the basement membrane. We present a case of a 59-year-old man with worsening blistering skin rash who was treated with vancomycin and piperacillin-tazobactam for pneumonia.

摘要

线状免疫球蛋白A(IgA)大疱性皮肤病(LABD)是一种罕见的自身免疫性疾病,可自发发生或由某些药物诱发,其中最常见的是万古霉素。LABD是一种表皮下大疱性疾病,通过检测沿基底膜的线状IgA带进行诊断。我们报告一例59岁男性患者,因肺炎接受万古霉素和哌拉西林-他唑巴坦治疗,出现水疱性皮疹且病情加重。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22df/7117611/fed140c0bc31/cureus-0012-00000007175-i01.jpg

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本文引用的文献

3
Vancomycin-induced Linear IgA Bullous Dermatosis: A Case Report and Review of the Literature.
Ann Dermatol. 2008 Jun;20(2):102-6. doi: 10.5021/ad.2008.20.2.102. Epub 2008 Jun 30.
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